SCHEMBL976981

SCHEMBL976981

NC1=COCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL490333 0.69
SCHEMBL3073245 0.67
SCHEMBL9569884 0.62
SCHEMBL4026431 0.57
SCHEMBL6873550 0.57
SCHEMBL16114785 0.53
SCHEMBL11954073 0.50
SCHEMBL3117258 0.50
SCHEMBL546296 0.50 MAPT (0.56)
SCHEMBL9086142 0.50

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 333 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3368089-A1 NANOPARTICLE FORMULATIONS FOR DELIVERY OF NUCLEIC ACID COMPLEXES TRANSLATE BIO MA, INC. (US) 2018-09-05 EP claimed
EP-2678079-B1 OXIDATIVE DYEING COMPOSITIONS COMPRISING AN 1-HEXYL/HEPTYL-4,5-DIAMINOPYRAZOLE AND A BENZO[1,3]DIOXOL-5-YLAMINE AND DERIVATIVES THEREOF NOXELL CORP (US) 2017-08-02 EP claimed
WO-2017075038-A1 NANOPARTICLE FORMULATIONS FOR DELIVERY OF NUCLEIC ACID COMPLEXES RANA THERAPEUTICS, INC. (US) 2017-05-04 WO claimed
CN-103458863-B Comprise 1-hexyl/heptyl-4, the oxidative coloration composition of 5-diamino-pyrazole and benzo [1,3] dioxole-5-base amine and derivative thereof THE PROCTER & GAMBLE CO. (US) 2016-05-04 CN claimed
CN-103443074-B Heterocyclic amine derivative HOFFMAN-LA ROCHE LTD. (CH) 2016-04-13 CN claimed
CN-103237801-B Quinoline or quinazoline derivatives having apoptosis-inducing activity on cells HANMI HOLDINGS Co.,Ltd. (KR) 2015-11-25 CN claimed
CN-105026411-A Ribonucleic acids with 4'-thio-modified nucleotides and related methods SHIRE HUMAN GENETIC THERAPIES 2015-11-04 CN claimed
CN-104922699-A LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF Eg5 AND VEGF GENES ALNYLAM PHARMACEUTICALS INC 2015-09-23 CN claimed
CN-104651408-A Lipid formulated siRNA targeted to PCSK9 gene ALNYLAM PHARMACEUTICALS INC 2015-05-27 CN claimed
CN-103458863-A Oxidative dyeing composition comprising 1-hexyl/heptyl-4,5-diaminopyrazole and benzo[1,3]dioxol-5-ylamine and derivatives thereof PROCTER & GAMBLE 2013-12-18 CN claimed
CN-103443074-A Heterocyclic amine derivatives HOFFMANN LA ROCHE 2013-12-11 CN claimed
CN-103237801-A Quinoline or quinazoline derivatives having apoptosis-inducing activity on cells HANMI HOLDINGS CO LTD 2013-08-07 CN claimed
CN-102458366-A Lipid formulated DSRNA targeting PCSK9 gene ALNYLAM PHARMACEUTICALS INC 2012-05-16 CN claimed
CN-102421900-A Lipid formulated compositions and methods for inhibiting expression of eg5 and vegf genes ALNYLAM PHARMACEUTICALS INC 2012-04-18 CN claimed
WO-2026102082-A1 ALKYLPHENYL SUBSTITUTED COMPOUNDS, COMPOSITIONS AND METHODS OF USE DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
EP-4727943-A1 INHIBITORS OF MET KINASE Celyn Therapeutics, Inc. (US) 2026-04-22 EP disclosed
US-12545636-B2 Acyclic lipids and methods of use thereof RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2026-02-10 US disclosed
CN-1478088-A Benzothiophene derivatives, process for their preparation and their use ά��ʵ�������޹�˾ 2004-02-25 CN disclosed
EP-1337528-A2 BENZOTHIOPHENE DERIVATIVE COMPOUNDS, PROCESS OF PREPARATION AND USE THEREOF LABORATORIOS VITA, S.A. (ES) 2003-08-27 EP disclosed
WO-2002044170-A2 BENZOTHIOPHENE DERIVATIVE COMPOUNDS, PROCESS OF PREPARATION AND USE THEREOF LABORATORIOS VITA, S.A. (ES) 2002-06-06 WO disclosed