Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 11/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769881 | 1.00 | HMGCR (0.82) | HMGCR | |
| SCHEMBL9769814 | 1.00 | HMGCR (0.82) | HMGCR | |
| SCHEMBL9769801 | 1.00 | HMGCR (0.82) | HMGCR | |
| SCHEMBL9769786 | 0.87 | HMGCR (0.74) | HMGCR | |
| SCHEMBL9802506 | 0.87 | HMGCR (0.74) | HMGCR | |
| SCHEMBL10555078 | 0.80 | HMGCR (0.82) | HMGCR | |
| SCHEMBL10437639 | 0.80 | HMGCR (0.82) | HMGCR | |
| SCHEMBL9769868 | 0.77 | HMGCR (0.61) | HMGCR | |
| SCHEMBL9769862 | 0.77 | HMGCR (0.61) | HMGCR | |
| SCHEMBL9860008 | 0.75 | HMGCR (0.48) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070206-A | INHIBITORS OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE; ANTICHOLESTEROL, ANTILIPEMIC | BRISTOL-MYERS COMPANY (US) | 1991-12-03 | — | — | US | disclosed |