Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 11/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860005 | 1.00 | HMGCR (0.48) | HMGCR | |
| SCHEMBL9859934 | 0.86 | HMGCR (0.38) | HMGCR | |
| SCHEMBL9859941 | 0.86 | HMGCR (0.38) | HMGCR | |
| SCHEMBL9769814 | 0.75 | HMGCR (0.82) | HMGCR | |
| SCHEMBL9769896 | 0.75 | HMGCR (0.82) | HMGCR | |
| SCHEMBL9769881 | 0.75 | HMGCR (0.82) | HMGCR | |
| SCHEMBL9769801 | 0.75 | HMGCR (0.82) | HMGCR | |
| SCHEMBL9855573 | 0.74 | HMGCR (0.48) | HMGCR | |
| SCHEMBL9860180 | 0.73 | MAPT (0.37) | — | |
| SCHEMBL9860172 | 0.73 | MAPT (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430129-A2 | Novel phenylethylene derivatives, processes for preparing the same and intermediates therefor | TANABE SEIYAKU CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |