Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.67 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.67 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.67 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.67 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.55 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683939 | 0.89 | ESR1 (0.62) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL21221663 | 0.89 | ESR1 (0.62) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL5710089 | 0.88 | ESR1 (0.61) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1038049 | 0.87 | ESR1 (0.72) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL4960394 | 0.87 | ESR1 (0.72) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1039666 | 0.87 | ESR1 (0.72) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1042180 | 0.87 | ESR1 (0.72) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11131748 | 0.87 | ESR1 (0.72) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1041010 | 0.87 | ESR1 (0.72) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1042703 | 0.87 | ESR1 (0.72) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019490-A | Chlorotrifluoroethylene Polymer | FUJI PHOTO FILM CO., LTD. (JP) | 1991-05-28 | — | — | US | disclosed |