Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 11/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL11113731 | 0.96 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL7959080 | 0.95 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL5049197 | 0.92 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL9443412 | 0.92 | TSHR (0.63) | TSHRHPGDALDH1A1CYP3A4ATM | |
| 1,4-Butanediol SCHEMBL9333775 | 0.90 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL1952425 | 0.90 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Methacrylic Acid SCHEMBL16797948 | 0.89 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Methacrylic Acid SCHEMBL27544199 | 0.89 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Ethylene Glycol SCHEMBL16819031 | 0.88 | TSHR (0.65) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL10457292 | 0.87 | TSHR (0.63) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028239-A | Vinyl polymers with hydrophilic and hydrophobic sections, haze-free gasoline | NALCO CHEMICAL COMPANY (US) | 1991-07-02 | — | — | US | claimed |
| US-5028239-A | Vinyl polymers with hydrophilic and hydrophobic sections, haze-free gasoline | NALCO CHEMICAL COMPANY (US) | 1991-07-02 | — | — | US | disclosed |