Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Carbinoxamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 known ✓ | P35367 | 4/20 | 0.81 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 0.81 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.81 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.81 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.81 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.81 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.81 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.81 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.81 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.81 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbinoxamine SCHEMBL29758299 | 1.00 | POLB (1.00) | POLBLMNACHRM2SLC6A2SLC6A4 | |
| Carbinoxamine SCHEMBL4223043 | 1.00 | POLB (1.00) | POLBLMNACHRM2SLC6A2SLC6A4 | |
| Rotoxamine SCHEMBL28665889 | 1.00 | POLB (1.00) | POLBLMNACHRM2SLC6A2SLC6A4 | |
| Carbinoxamine SCHEMBL97704 | 1.00 | POLB (1.00) | POLBLMNACHRM2SLC6A2SLC6A4 | |
| Rotoxamine SCHEMBL6312191 | 0.90 | CHRM2 (0.83) | POLBLMNACHRM2SLC6A2SLC6A4 | |
| Carbinoxamine SCHEMBL29414093 | 0.90 | CHRM2 (1.00) | POLBLMNACHRM2SLC6A2SLC6A4 | |
| Carbinoxamine SCHEMBL29881788 | 0.90 | CHRM2 (1.00) | POLBLMNACHRM2SLC6A2SLC6A4 | |
| Carbinoxamine SCHEMBL5070 | 0.90 | CHRM2 (1.00) | POLBLMNACHRM2SLC6A2SLC6A4 | |
| Rotoxamine SCHEMBL29485023 | 0.90 | CHRM2 (1.00) | POLBLMNACHRM2SLC6A2SLC6A4 | |
| Rotoxamine SCHEMBL141389 | 0.90 | CHRM2 (1.00) | POLBLMNACHRM2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2936 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724114-A1 | CYANOACRYLATE ADHESIVE KITS | Chemence, Inc. (US) | 2026-04-15 | — | — | EP | claimed |
| WO-2026041855-A1 | CYANOACRYLATE ADHESIVE KITS | CHEMENCE, INC. (US) | 2026-02-26 | — | — | WO | claimed |
| US-20260033494-A1 | PLANT ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF | TEXAS A & M UNIV SYS (US) | 2026-02-05 | — | — | US | claimed |
| US-12458025-B2 | Plant antimicrobial compositions and methods of use thereof | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 2025-11-04 | — | — | US | claimed |
| US-20240282425-A1 | AUTHENTICATION METHODS AND SYSTEMS FOR DISPENSED PRESCRIPTIONS | LOW GORDON KEITH (US) | 2024-08-22 | — | — | US | claimed |
| US-20240225003-A1 | PLANT ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF | THE TEXAS A&M UNIVERSITY SYSTEM | 2024-07-11 | — | — | US | claimed |
| WO-2024028324-A1 | MOLECULES FOR THE PREVENTION AND TREATMENT OF NEUROMUSCULAR DISORDERS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2024-02-08 | — | — | WO | claimed |
| EP-3993856-A1 | AEROSOL DELIVERY DEVICES AND METHODS OF USING SAME | Airja, Inc. (US) | 2022-05-11 | — | — | EP | claimed |
| WO-2021243003-A1 | PLANT ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2021-12-02 | — | — | WO | claimed |
| US-20210368795-A1 | PLANT ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF | THE TEXAS A&M UNIVERSITY SYSTEM | 2021-12-02 | — | — | US | claimed |
| EP-0608322-A1 | ENHANCED SKIN PENETRATION SYSTEM FOR IMPROVED TOPICAL DELIVERY OF DRUGS | RICHARDSON-VICKS, INC. (US) | 1994-08-03 | — | — | EP | claimed |
| EP-0582380-A1 | Dry granulation using a fluidized bed | McNEIL-PPC, INC. (US) | 1994-02-09 | — | — | EP | claimed |
| WO-1994002176-A1 | PHARMACEUTICAL COMPOSITION FOR TOPICAL USE CONTAINING A CROSSLINKED CATIONIC POLYMER AND AN ALKOXYLATED ETHER | THE PROCTER & GAMBLE COMPANY (US) | 1994-02-03 | — | — | WO | claimed |
| CN-1072863-A | Be used to improve the dermal osmosis system of the reinforcement of medicine localized delivery | RICHARDSON VICKS INC (US) | 1993-06-09 | — | — | CN | claimed |
| CN-1072602-A | Improve the enhanced dermal osmosis system of the local conveying of medicine | RICHARDSON VICKS INC (US) | 1993-06-02 | — | — | CN | claimed |
| WO-1993007903-A1 | ENHANCED SKIN PENETRATION SYSTEM FOR IMPROVED TOPICAL DELIVERY OF DRUGS | RICHARDSON-VICKS, INC. (US) | 1993-04-29 | — | — | WO | claimed |
| US-4952402-A | EDIBLE TASTE-MASKED DRUGS; MICROMATRIX ACTIVE MATERIAL COATED WITH NONTOXIC POLYMER; LIQUIDS; TABLETS | ELAN CORPORATION, P.L.C. (IE) | 1990-08-28 | — | — | US | claimed |
| EP-0351897-A2 | Skin penetration system for salts of amine-functional drugs | THE PROCTER & GAMBLE COMPANY (US) | 1990-01-24 | — | — | EP | claimed |
| EP-0189861-A2 | Percutaneous absorption accelerator for ionic water-soluble medicine | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1986-08-06 | — | — | EP | claimed |
| US-4269835-A | Nasal composition for relieving nasal distress | WHITTLE BARRY J | 1981-05-26 | — | — | US | claimed |