Carbinoxamine

Carbinoxamine

SCHEMBL29414093

CN(C)CCOC(c1ccc(Cl)cc1)c1ccccn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

HRH1

The experimentally established mechanism targets of Carbinoxamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 known ✓ P35367 6/20 1.00
CHRM2 P08172 8/20 1.00
SLC6A2 P23975 8/20 1.00
SLC6A4 P31645 8/20 1.00
SLC6A3 Q01959 7/20 1.00
KCNH2 Q12809 6/20 1.00
ADRA2B P18089 5/20 1.00
HRH3 Q9Y5N1 5/20 1.00
LMNA P02545 5/20 1.00
CYP2D6 P10635 4/20 1.00
CYP2C19 P33261 1/20 1.00
POLB P06746 1/20 0.81
CHRM1 P11229 6/20 0.62
HTR2A P28223 4/20 0.62
SCN1A P35498 4/20 0.62
SCN2A Q99250 4/20 0.62
SCN3A Q9NY46 4/20 0.62
CHRM5 P08912 3/20 0.62
HRH2 P25021 3/20 0.62
ADRA2A P08913 3/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbinoxamine SCHEMBL29881788 1.00 CHRM2 (1.00) CHRM2SLC6A2SLC6A4SLC6A3HRH1
Rotoxamine SCHEMBL29485023 1.00 CHRM2 (1.00) CHRM2SLC6A2SLC6A4SLC6A3HRH1
Rotoxamine SCHEMBL141389 1.00 CHRM2 (1.00) CHRM2SLC6A2SLC6A4SLC6A3HRH1
Carbinoxamine SCHEMBL5070 1.00 CHRM2 (1.00) CHRM2SLC6A2SLC6A4SLC6A3HRH1
Carbinoxamine SCHEMBL8709373 0.99 CHRM2 (0.97) CHRM2SLC6A2SLC6A4SLC6A3HRH1
Carbinoxamine SCHEMBL662375 0.96 CHRM2 (0.93) CHRM2SLC6A2SLC6A4SLC6A3HRH1
Carbinoxamine SCHEMBL6626762 0.95 CHRM2 (0.91) CHRM2SLC6A2SLC6A4SLC6A3HRH1
Carbinoxamine SCHEMBL9095143 0.95 CHRM2 (0.91) CHRM2SLC6A2SLC6A4SLC6A3HRH1
Carbinoxamine SCHEMBL17685697 0.92 CHRM2 (0.84) CHRM2SLC6A2SLC6A4SLC6A3HRH1
Carbinoxamine SCHEMBL4074917 0.91 CHRM2 (0.83) CHRM2SLC6A2SLC6A4SLC6A3HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4247331-B1 ORODISPERSIBLE POWDER COMPOSITION COMPRISING AN ANTIHISTAMINE COMPOUND BIOPHARMA SYNERGIES S L (ES) 2025-10-08 EP claimed
EP-3682872-B1 LIQUISOFT CAPSULES PATHEON SOFTGELS INC (US) 2024-01-03 EP claimed
EP-4731194-A1 MATERIALS AND METHODS FOR MITIGATING THE PRESENCE OF NITROSAMINES IN PACKAGING USING AN ACTIVE AGENT CSP Technologies, Inc. (US) 2026-04-29 EP disclosed
WO-2025264260-A1 MATERIALS AND METHODS FOR MITIGATING THE PRESENCE OF NITROSAMINES IN PACKAGING USING AN ACTIVE AGENT CSP TECHNOLOGIES, INC. (US) 2025-12-26 WO disclosed
EP-4491193-A2 ANTI-CD154 ANTIBODIES AND USES THEREOF Tonix Pharma Limited (IE) 2025-01-15 EP disclosed
WO-2024263560-A1 MATERIALS AND METHODS FOR MITIGATING THE PRESENCE OF NITROSAMINES IN PACKAGING USING AN ACTIVE AGENT CSP TECHNOLOGIES, INC. (US) 2024-12-26 WO disclosed
EP-3993876-B1 ANTI-CD154 ANTIBODIES AND USES THEREOF TONIX PHARMA LTD (IE) 2024-08-28 EP disclosed
CN-117835972-A Novel compositions comprising immunomodulatory drugs 南爱克萨股份公司 2024-04-05 CN disclosed
US-20230148946-A1 METHODS OF DETECTING ALLERGIC REACTIONS IN SUBJECTS USING MICROCHANNEL DELIVERY DEVICES AQUAVIT PHARMACEUTICALS INC (US) 2023-05-18 US disclosed
EP-4178589-A1 METHODS OF PROTECTING CELLS FROM INSULTS Musc Foundation for Research Development (US) 2023-05-17 EP disclosed
CN-116063137-A Synthesis method for synthesizing chiral 2-pyridyl aryl methanol by iridium catalysis 中国科学院大连化学物理研究所 2023-05-05 CN disclosed
CN-115701989-A Co-milled active-containing products comprising surface-reacted calcium carbonate OMYA国际股份公司 2023-02-14 CN disclosed
US-20220380478-A1 ANTI-CD154 ANTIBODIES AND USES THEREOF TONIX PHARMACEUTICALS HOLDING CORP. 2022-12-01 US disclosed
US-20220362404-A1 MODULATION OF CELLULAR VIABILITY MACQUARIE UNIVERSITY (AU) 2022-11-17 US disclosed
EP-3993876-A1 ANTI-CD154 ANTIBODIES AND USES THEREOF Tonix Pharma Limited (IE) 2022-05-11 EP disclosed
EP-3962455-A1 NEW PHARMACEUTICAL COMPOSITION FOR DRUG DELIVERY Orexo AB (SE) 2022-03-09 EP disclosed