SCHEMBL9770302

SCHEMBL9770302

Clc1ccc(OCCCCOc2ccc(Cl)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH3A1 P30838 1/20 0.62
DRD4 P21917 4/20 0.59
DRD2 P14416 3/20 0.59
DRD3 P35462 3/20 0.59
KCNH2 Q12809 2/20 0.59
HRH3 Q9Y5N1 7/20 0.58
ALDH1A1 P00352 1/20 0.58
KCNA3 P22001 1/20 0.55
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11815991 0.97 HRH3 (0.61) ALDH3A1DRD4DRD2DRD3KCNH2
SCHEMBL30514014 0.97 HRH3 (0.61) ALDH3A1DRD4DRD2DRD3KCNH2
SCHEMBL9770319 0.94 DRD4 (0.59) ALDH3A1DRD4DRD2DRD3KCNH2
SCHEMBL3446688 0.93 ALDH3A1 (0.56) ALDH3A1DRD4DRD2DRD3KCNH2
SCHEMBL1345118 0.92 MAOB (0.57) ALDH3A1DRD4DRD2DRD3KCNH2
SCHEMBL1115575 0.91 HRH3 (0.56) ALDH3A1DRD4DRD2DRD3KCNH2
SCHEMBL2411188 0.90 DRD4 (0.55) ALDH3A1DRD4DRD2DRD3KCNH2
SCHEMBL11442484 0.89 ALDH3A1 (0.53) ALDH3A1DRD4DRD2DRD3KCNH2
SCHEMBL4028552 0.89 ALDH3A1 (0.53) ALDH3A1DRD4DRD2DRD3KCNH2
SCHEMBL1045733 0.89 ALDH3A1 (0.53) ALDH3A1DRD4DRD2DRD3KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4985393-A Bis/hydroxyphenylthio/ Compounds KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1991-01-15 US disclosed
US-4981836-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1991-01-01 US disclosed
EP-0373561-A2 Heat sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-06-20 EP disclosed
US-4855278-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-08-08 US disclosed
US-4835133-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-30 US disclosed
US-4701565-A REACTING ALCOHOL WITH ORGANIC SULFONYL HALIDE TO FORM SULFONATE, REACTING SULFONATE WITH A PHENOL FUJI PHOTO FILM CO., LTD. (JP) 1987-10-20 US disclosed