Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10405654 | 1.00 | TRPV1 (0.50) | TRPV1KMT2ACTSKMAPTPTGS1 | |
| SCHEMBL9419767 | 1.00 | TRPV1 (0.50) | TRPV1KMT2ACTSKMAPTPTGS1 | |
| SCHEMBL10405653 | 1.00 | TRPV1 (0.50) | TRPV1KMT2ACTSKMAPTPTGS1 | |
| SCHEMBL11484335 | 1.00 | TRPV1 (0.50) | TRPV1KMT2ACTSKMAPTPTGS1 | |
| SCHEMBL31678748 | 0.98 | TRPV1 (0.51) | TRPV1KMT2ACTSKMAPTPTGS1 | |
| SCHEMBL6263109 | 0.98 | TRPV1 (0.51) | TRPV1KMT2ACTSKMAPTPTGS1 | |
| SCHEMBL6263113 | 0.98 | TRPV1 (0.51) | TRPV1KMT2ACTSKMAPTPTGS1 | |
| SCHEMBL10921446 | 0.91 | CTSK (0.45) | TRPV1KMT2ACTSKMAPTPTGS1 | |
| SCHEMBL10921443 | 0.91 | CTSK (0.45) | TRPV1KMT2ACTSKMAPTPTGS1 | |
| SCHEMBL11484782 | 0.89 | CTSK (0.43) | TRPV1KMT2ACTSKMAPTPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988732-A | Antitumor agents, skin disorders | EISAI CO., LTD. (JP) | 1991-01-29 | — | — | US | disclosed |
| US-4917829-A | ANTICANCER AGENT | EISAI CO., LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| US-4199531-A | Intermediates for the production of quinones | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-04-22 | — | — | US | disclosed |