SCHEMBL9770451

SCHEMBL9770451

Cc1cc(O)n2nc(CCO)nc2n1

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.60
ALDH1A1 P00352 1/20 0.57
HTT P42858 1/20 0.57
PDE10A Q9Y233 16/20 0.44
KDM4E B2RXH2 1/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9770259 0.91 ALDH1A1 (0.62) RECQLALDH1A1HTTPDE10AKDM4E
SCHEMBL9770324 0.89 ALDH1A1 (0.73) RECQLALDH1A1HTTPDE10AKDM4E
SCHEMBL7100505 0.87 RECQL (0.54) RECQLALDH1A1HTTPDE10AKDM4E
SCHEMBL1681608 0.83 RECQL (0.54) RECQLALDH1A1HTTPDE10AKDM4E
SCHEMBL9822091 0.83 RECQL (0.58) RECQLALDH1A1HTTPDE10AKDM4E
SCHEMBL9822087 0.83 RECQL (0.58) RECQLALDH1A1HTTPDE10AKDM4E
SCHEMBL9140975 0.82 RECQL (0.57) RECQLALDH1A1HTTPDE10AKDM4E
SCHEMBL6233107 0.82 RECQL (0.53) RECQLALDH1A1HTTPDE10AKDM4E
SCHEMBL9139590 0.82 RECQL (0.53) RECQLALDH1A1HTTPDE10AKDM4E
SCHEMBL18358398 0.82 RECQL (0.53) RECQLALDH1A1HTTPDE10AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4011083-A SURFACE SENSITIVE SILVER HALIDE EMULSION CONTAINING A SILVER COMPLEXING AZAINDENE TO REDUCE DESENSITIZATION OF OPTICAL SENSITIZING DYE INCORPORATED THEREIN EASTMAN KODAK COMPANY (US) 1977-03-08 US claimed
US-5015567-A Sensitization In The Presence Of An Organic Thioether Or A Tetra-substituted Thiourea And A Triazolopyrimidine Stabilizer FUJI PHOTO FILM CO., LTD. (JP) 1991-05-14 US disclosed
US-4724200-A CRYSTAL STRUCTURE EASTMAN KODAK COMPANY (US) 1988-02-09 US disclosed
US-4680255-A Emulsions and photographic elements containing silver halide grains having tetrahexahedral crystal faces EASTMAN KODAK COMPANY (US) 1987-07-14 US disclosed
US-4680254-A Emulsions and photographic elements containing silver halide grains having hexoctamedral crystal faces EASTMAN KODAK COMPANY (US) 1987-07-14 US disclosed
US-4680256-A Emulsions and photographic elements containing silver halide grains having trisoctahedra crystal faces EASTMAN KODAK COMPANY (US) 1987-07-14 US disclosed
US-4307186-A IMPROVED ANTIFOGGING AND FLATTENING OF SILVER HALIDE EMULSION WITH TETRAAZAINDENES PENTAAZAINDENES OR TRIAZAINDOLIZINES AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1981-12-22 US disclosed
US-4011083-A SURFACE SENSITIVE SILVER HALIDE EMULSION CONTAINING A SILVER COMPLEXING AZAINDENE TO REDUCE DESENSITIZATION OF OPTICAL SENSITIZING DYE INCORPORATED THEREIN EASTMAN KODAK COMPANY (US) 1977-03-08 US disclosed