Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.61 |
| ▸ | STAT6 | P42226 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15854869 | 0.89 | SLC6A3 (0.70) | AHRSLC6A3TSHRKDM4EABCB11 | |
| Dihydroxydiphenyl-Pyridyl Methane SCHEMBL29356385 | 0.87 | SLC6A3 (0.70) | AHRSLC6A3TSHRKDM4EABCB11 | |
| Dihydroxydiphenyl-Pyridyl Methane SCHEMBL3615825 | 0.87 | SLC6A3 (0.70) | AHRSLC6A3TSHRKDM4EABCB11 | |
| SCHEMBL14164965 | 0.84 | SLC6A3 (0.78) | AHRSLC6A3TSHRKDM4EABCB11 | |
| SCHEMBL2021127 | 0.83 | SLC6A3 (0.89) | AHRSLC6A3TSHRKDM4EABCB11 | |
| SCHEMBL14165003 | 0.83 | KDM4E (0.89) | AHRSLC6A3TSHRKDM4EABCB11 | |
| SCHEMBL15854856 | 0.83 | AHR (0.60) | AHRSLC6A3TSHRKDM4EABCB11 | |
| Dihydroxydiphenyl-Pyridyl Methane SCHEMBL2021125 | 0.81 | KDM4E (0.64) | AHRSLC6A3TSHRKDM4EABCB11 | |
| SCHEMBL29608919 | 0.81 | SLC6A3 (0.61) | AHRSLC6A3TSHRKDM4EABCB11 | |
| SCHEMBL15854862 | 0.81 | CYP3A4 (0.53) | AHRSLC6A3TSHRKDM4EABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046270-A1 | Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them | INTERx RESEARCH CORPORATION (US) | 1982-02-24 | — | — | EP | claimed |
| US-20140186872-A1 | BISACODYL AND ITS ANALOGUES AS DRUGS FOR USE IN THE TREATMENT OF CANCER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE- CNRS (FR) | 2014-07-03 | — | — | US | disclosed |
| US-20140186872-A1 | BISACODYL AND ITS ANALOGUES AS DRUGS FOR USE IN THE TREATMENT OF CANCER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE- CNRS (FR) | 2014-07-03 | — | — | US | disclosed |
| US-20140186872-A1 | BISACODYL AND ITS ANALOGUES AS DRUGS FOR USE IN THE TREATMENT OF CANCER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE- CNRS (FR) | 2014-07-03 | — | — | US | disclosed |
| EP-2717875-A2 | BISACODYL AND ANALOGUES AS DRUGS FOR TREATING CANCER | Université de Strasbourg (FR) | 2014-04-16 | — | — | EP | disclosed |
| WO-2012168885-A2 | BISACODYL AND ANALOGUES AS DRUGS FOR TREATING CANCER | UNIVERSITÉ DE STRASBOURG (FR) | 2012-12-13 | — | — | WO | disclosed |
| WO-2012168885-A2 | BISACODYL AND ANALOGUES AS DRUGS FOR TREATING CANCER | UNIVERSITÉ DE STRASBOURG (FR) | 2012-12-13 | — | — | WO | disclosed |
| US-5001115-A | Prodrugs of biologically active hydroxyaromatic compounds | UNIVERSITY OF FLORIDA (US) | 1991-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140186872-A1 | BISACODYL AND ITS ANALOGUES AS DRUGS FOR USE IN THE TREATMENT OF CANCER | CCND1, DEGS1, MCL1 | AHR 1541/4885SLC6A3 1219/4885TSHR 2251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.