Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 4/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL915801 | 0.96 | CA4 (0.45) | HSD17B2HSD17B1ALOX15ACHEMTNR1A | |
| SCHEMBL914300 | 0.96 | CA4 (0.45) | HSD17B2HSD17B1ALOX15ACHEMTNR1A | |
| SCHEMBL19275026 | 0.96 | CA4 (0.45) | HSD17B2HSD17B1ALOX15ACHEMTNR1A | |
| SCHEMBL4324691 | 0.95 | HSD17B2 (0.47) | HSD17B2HSD17B1ALOX15MTNR1AMTNR1B | |
| SCHEMBL9763422 | 0.95 | HSD17B2 (0.47) | HSD17B2HSD17B1ALOX15MTNR1AMTNR1B | |
| SCHEMBL17372968 | 0.95 | HSD17B2 (0.47) | HSD17B2HSD17B1ALOX15MTNR1AMTNR1B | |
| SCHEMBL13136850 | 0.95 | HSD17B2 (0.47) | HSD17B2HSD17B1ALOX15MTNR1AMTNR1B | |
| SCHEMBL12463079 | 0.95 | HSD17B2 (0.47) | HSD17B2HSD17B1ALOX15MTNR1AMTNR1B | |
| SCHEMBL3442214 | 0.95 | HSD17B2 (0.47) | HSD17B2HSD17B1ALOX15MTNR1AMTNR1B | |
| SCHEMBL14163837 | 0.94 | ACHE (0.50) | HSD17B2HSD17B1ALOX15ACHEMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011939-A | Hydroxy functionalized arylamine compounds | XEROX CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |