Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770924 | 0.86 | PDGFRB (0.40) | ALDH1A1KMT2AGAAMAPTLMNA | |
| SCHEMBL9770873 | 0.85 | KMT2A (0.33) | ALDH1A1KMT2AGAAGLAMAPT | |
| SCHEMBL9770928 | 0.79 | ALDH1A1 (0.44) | ALDH1A1KMT2AGAAGLAUSP2 | |
| SCHEMBL10513330 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KMT2AGAAGLAUSP2 | |
| SCHEMBL9770869 | 0.72 | HDAC3 (0.38) | ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL9770859 | 0.70 | ALDH1A1 (0.48) | ALDH1A1KMT2AGAAGLAUSP2 | |
| SCHEMBL30954114 | 0.68 | ALDH1A1 (0.51) | ALDH1A1KMT2AGAAGLAUSP2 | |
| SCHEMBL5254611 | 0.67 | ALDH1A1 (0.47) | ALDH1A1KMT2AGAAGLAUSP2 | |
| SCHEMBL9094743 | 0.66 | ALDH1A1 (0.34) | ALDH1A1KMT2AGAAGLAMAPT | |
| SCHEMBL9824163 | 0.66 | KMT2A (0.35) | ALDH1A1KMT2AGAAGLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039331-A | Condensed heterocyclic derivatives and herbicides | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-13 | — | — | US | disclosed |
| EP-0304920-A2 | Condensed heterocyclic derivatives, process for their production and herbicides | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-03-01 | — | — | EP | disclosed |