Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.59 |
| ▸ | SYK | P43405 | 1/20 | 0.53 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10521190 | 1.00 | REN (0.59) | RENSYKHTRA1CTSL | |
| SCHEMBL8269721 | 0.85 | REN (0.53) | RENSYKCTSL | |
| SCHEMBL12631595 | 0.85 | REN (0.53) | RENSYKCTSL | |
| SCHEMBL13256207 | 0.85 | REN (0.53) | RENSYKCTSL | |
| SCHEMBL9770965 | 0.85 | REN (0.56) | REN | |
| SCHEMBL6486670 | 0.85 | REN (0.54) | RENHTRA1CTSL | |
| SCHEMBL5741475 | 0.84 | KLK5 (0.61) | SYKCTSL | |
| SCHEMBL15483355 | 0.84 | SYK (0.67) | SYKCTSL | |
| SCHEMBL1600915 | 0.84 | KLK5 (0.61) | SYKCTSL | |
| SCHEMBL7364676 | 0.83 | REN (0.67) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045537-A | Treating Diseases Caused by Retroviruses | SANDOZ LTD. (CH) | 1991-09-03 | — | — | US | disclosed |