Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 12/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 6/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529162 | 0.88 | DRD1 (0.65) | DRD1SLC6A2SLC6A4SLC6A3DRD5 | |
| SCHEMBL9771971 | 0.86 | DRD1 (0.44) | DRD1DRD5DRD2KDM4EALPL | |
| SCHEMBL9529544 | 0.85 | DRD1 (0.68) | DRD1SLC6A2SLC6A4SLC6A3DRD5 | |
| SCHEMBL9530499 | 0.84 | DRD1 (0.62) | DRD1SLC6A2SLC6A4SLC6A3DRD5 | |
| SCHEMBL9772045 | 0.84 | DRD1 (0.61) | DRD1SLC6A2SLC6A4SLC6A3DRD5 | |
| SCHEMBL9528451 | 0.84 | DRD1 (0.61) | DRD1SLC6A2SLC6A4SLC6A3DRD5 | |
| SCHEMBL9529675 | 0.83 | DRD1 (0.65) | DRD1SLC6A2SLC6A4SLC6A3DRD5 | |
| SCHEMBL9532321 | 0.82 | DRD1 (0.59) | DRD1SLC6A2SLC6A4SLC6A3DRD5 | |
| SCHEMBL10691047 | 0.81 | DRD1 (0.75) | DRD1SLC6A2SLC6A4SLC6A3DRD5 | |
| SCHEMBL9771934 | 0.81 | DRD1 (0.58) | DRD1SLC6A2SLC6A4SLC6A3DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017571-A | Prodrugs, mental disorders | NOVO NORDISK A/S (DK) | 1991-05-21 | — | — | US | disclosed |
| EP-0331130-A1 | Carbamic acid ester of substituted 7-hydroxy-2,3,4,5-tetrahydro-1H-3-benzazepines | NOVO NORDISK A/S (DK) | 1989-09-06 | — | — | EP | disclosed |