⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15928062 | 0.72 | HIF1A (0.39) | — | |
| SCHEMBL1442558 | 0.71 | — | — | |
| SCHEMBL2267693 | 0.69 | — | — | |
| SCHEMBL3990277 | 0.69 | HIF1A (0.36) | — | |
| Iodide SCHEMBL9065199 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL31309953 | 0.67 | HIF1A (0.33) | — | |
| SCHEMBL3974293 | 0.67 | — | — | |
| SCHEMBL490935 | 0.65 | — | — | |
| SCHEMBL64209 | 0.65 | — | — | |
| SCHEMBL14801159 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6979431-B2 | Method for labelling technetium or rhenium using borohydride exchange resin | KOREA ATOMIC ENERGY RESEARCH INSTITUTE (KR) | 2005-12-27 | — | — | US | claimed |
| US-20030194365-A1 | Method for labelling technetium or rhenium using borohydride exchange resin | KOREA ATOMIC ENERGY RESEARCH INSTITUTE (KR) | 2003-10-16 | — | — | US | claimed |
| EP-1379499-B1 | NEW DIAMINEDITHIOL DERIVATIVES AND RADIORHENIUM OR RADIOTECHNETIUM COMPLEX THEREOF; A LIVER CANCER-TREATING COMPOSITION COMPRISING THE RADIORHENIUM COMPLEX AND LIPIODOL; AND A KIT FOR PREPARATION OF THE LIVER CANCER-TREATING COMPOSITION | SEOUL NAT UNIV IND FOUNDATION (KR) | 2011-05-18 | — | — | EP | disclosed |
| US-7875287-B2 | 99mTc-8-[3-({2-[4-(2-methoxy-phenyl)-piperazine -1-yl]-ethyl}-pyridin-2-yl-amino)-propyl]-[1,2,5,8]dithiadiazecan-6-one; 5-HT1A selective serotonin receptors;receptivity; nonhydrolyzing; radiopharmaceuticals;scanning the brain; neurogenitive deseases; nervous system disorders | KOREA ATOMIC ENERGY RESEARCH INSTITUTE (KR) | 2011-01-25 | — | — | US | disclosed |
| EP-1379499-A4 | NEW DIAMINEDITHIOL DERIVATIVES AND RADIORHENIUM OR RADIOTECHNETIUM COMPLEX THEREOF; A LIVER CANCER-TREATING COMPOSITION COMPRISING THE RADIORHENIUM COMPLEX AND LIPIODOL; AND A KIT FOR PREPARATION OF THE LIVER CANCER-TREATING COMPOSITION | SEOUL NAT UNIV IND FOUNDATION (KR) | 2009-08-05 | — | — | EP | disclosed |
| US-20070036715-A1 | 99mTc-8-[3-({2-[4-(2-methoxy-phenyl)-piperazine -1-yl]-ethyl}-pyridin-2-yl-amino)-propyl]-[1,2,5,8]dithiadiazecan-6-one; 5-HT1A selective serotonin receptors;receptivity; nonhydrolyzing; radiopharmaceuticals;scanning the brain; neurogenitive deseases; nervous system disorders | KOREA ATOMIC ENERGY RESEARCH INSTITUTE (KR) | 2007-02-15 | — | — | US | disclosed |
| US-7067508-B2 | Diaminedithiol derivatives and radiorhenium or radiotechnetium complex thereof; a liver cancer-treating composition comprising the radiorhenium complex and lipiodol; and a kit for preparation of the liver cancer-treating composition | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2006-06-27 | — | — | US | disclosed |
| US-6979431-B2 | Method for labelling technetium or rhenium using borohydride exchange resin | KOREA ATOMIC ENERGY RESEARCH INSTITUTE (KR) | 2005-12-27 | — | — | US | disclosed |
| US-6958141-B2 | Rhenium and technetium complexes containing a hypoxia-localizing moiety | BRACCO INTERNATIONAL B.V. (NL) | 2005-10-25 | — | — | US | disclosed |
| US-6936240-B2 | Method for the preparation of technetium or rhenium complex for radiopharmaceuticals | KOREA ATOMIC ENERGY RESEARCH INSTITUTE (KR) | 2005-08-30 | — | — | US | disclosed |
| US-6888019-B1 | Method of preparing rhenium complex using borohydride exchange resin | KOREA ATOMIC ENERGY RESEARCH INSTITUTE (KR) | 2005-05-03 | — | — | US | disclosed |
| EP-0544412-B1 | Rhenium and technetium complexes containing a hypoxia-localizing moiety | BRACCO INT BV (NL) | 1997-07-23 | — | — | EP | disclosed |
| US-5155227-A | Compounds for site-enhanced delivery of radionuclides | UNIVERSITY OF FLORIDA (US) | 1992-10-13 | — | — | US | disclosed |
| US-5136038-A | Radiopharmaceuticals and chelating agents useful in their preparation | UNIVERSITY OF FLORIDA (US) | 1992-08-04 | — | — | US | disclosed |
| US-4963688-A | Compounds for site-enhanced delivery of radionuclides and uses thereof | UNIVERSITY OF FLORIDA (US) | 1990-10-16 | — | — | US | disclosed |
| US-4963682-A | Novel radiopharmaceuticals and chelating agents useful in their preparation | UNIVERSITY OF FLORIDA (US) | 1990-10-16 | — | — | US | disclosed |
| EP-0191788-A1 | NOVEL RADIOPHARMACEUTICALS AND CHELATING AGENTS USEFUL IN THEIR PREPARATION | UNIVERSITY OF FLORIDA (US) | 1986-08-27 | — | — | EP | disclosed |
| EP-0187832-A1 | COMPOUNDS FOR SITE-ENHANCED DELIVERY OF RADIONUCLIDES AND USES THEREOF | UNIVERSITY OF FLORIDA (US) | 1986-07-23 | — | — | EP | disclosed |
| WO-1986000897-A1 | NOVEL RADIOPHARMACEUTICALS AND CHELATING AGENTS USEFUL IN THEIR PREPARATION | UNIVERSITY OF FLORIDA (US) | 1986-02-13 | — | — | WO | disclosed |
| WO-1986000898-A1 | COMPOUNDS FOR SITE-ENHANCED DELIVERY OF RADIONUCLIDES AND USES THEREOF | UNIVERSITY OF FLORIDA (US) | 1986-02-13 | — | — | WO | disclosed |