Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.48 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964605 | 1.00 | SIGMAR1 (0.48) | SIGMAR1SLC9A3FKBP1AHSD11B1LMNA | |
| SCHEMBL9772337 | 0.86 | SIGMAR1 (0.64) | SIGMAR1LMNAOPRM1OPRD1OPRK1 | |
| SCHEMBL9251914 | 0.80 | SLC9A3 (0.43) | SIGMAR1SLC9A3HSD11B1LMNAOPRM1 | |
| SCHEMBL9772450 | 0.79 | SIGMAR1 (0.61) | SIGMAR1SLC9A3HSD11B1OPRM1OPRD1 | |
| SCHEMBL7963090 | 0.79 | SIGMAR1 (0.61) | SIGMAR1SLC9A3HSD11B1OPRM1OPRD1 | |
| SCHEMBL9772623 | 0.78 | SIGMAR1 (0.61) | SIGMAR1LMNAOPRM1OPRD1OPRK1 | |
| SCHEMBL9772385 | 0.74 | SIGMAR1 (0.47) | SIGMAR1SLC9A3LMNAOPRM1OPRD1 | |
| SCHEMBL7962240 | 0.74 | SIGMAR1 (0.47) | SIGMAR1SLC9A3LMNAOPRM1OPRD1 | |
| 1,2-Dichlorobenzene SCHEMBL9643933 | 0.73 | SIGMAR1 (0.54) | SIGMAR1SLC9A3OPRM1OPRD1OPRK1 | |
| SCHEMBL9512792 | 0.72 | SIGMAR1 (0.41) | SIGMAR1SLC9A3HSD11B1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043347-A | Indanes and analgesic compositions and methods thereof | ROUSSEL UCLAF (FR) | 1991-08-27 | — | — | US | disclosed |