SCHEMBL9772433

SCHEMBL9772433

O=C(c1ccccc1)c1ccc(CS(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.67
HSD17B10 Q99714 1/20 0.67
MAPT P10636 4/20 0.56
HSD11B1 P28845 4/20 0.50
ALDH1A1 P00352 2/20 0.50
MMP1 P03956 1/20 0.49
MMP2 P08253 1/20 0.49
MMP3 P08254 1/20 0.49
MMP9 P14780 1/20 0.49
MMP8 P22894 1/20 0.49
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA9 Q16790 1/20 0.49
CA14 Q9ULX7 1/20 0.49
SRD5A2 P31213 1/20 0.48
HDAC1 Q13547 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6265091 0.81 ALDH1A1 (0.54) TSHRHSD17B10MAPTALDH1A1CA12
Benzylsulfonylbenzene SCHEMBL780337 0.80 TSHR (0.68) TSHRHSD17B10MAPTALDH1A1MMP1
SCHEMBL3916464 0.80 POLB (0.62) TSHRHSD17B10MAPTALDH1A1CA12
SCHEMBL9500508 0.80 ALDH1A1 (0.52) TSHRHSD17B10MAPTALDH1A1CA12
SCHEMBL11827401 0.80 TSHR (1.00) TSHRHSD17B10MAPTCA12CA1
SCHEMBL9772279 0.80 RCE1 (0.56) TSHRHSD17B10MAPTALDH1A1CA12
SCHEMBL11114440 0.79 MAPT (0.61) TSHRHSD17B10MAPTHSD11B1MMP2
SCHEMBL8556017 0.79 TSHR (0.58) TSHRHSD17B10MAPTKMT2A
SCHEMBL28108048 0.79 TSHR (0.58) TSHRHSD17B10MAPTHSD11B1ALDH1A1
SCHEMBL9500502 0.79 ALDH1A1 (0.50) TSHRHSD17B10MAPTALDH1A1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5026740-A For transparent or pigmented mixtures FRATELLI LAMBERTI S.P.A. (IT) 1991-06-25 US disclosed
EP-0192967-B1 SULPHURATED DERIVATIVES OF AROMATIC-ALIPHATIC AND ALIPHATIC KETONES AS POLYMERISATION PHOTOINITIATORS FRATELLI LAMBERTI S.p.A. (IT) 1990-08-01 EP disclosed
EP-0192967-A1 Sulphurated derivatives of aromatic-aliphatic and aliphatic ketones as polymerisation photoinitiators FRATELLI LAMBERTI S.p.A. (IT) 1986-09-03 EP disclosed