Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10980506 | 0.86 | PTGS1 (0.47) | ALDH1A1SMN1; SMN2PTGS1MAPTCXCR1 | |
| SCHEMBL27634032 | 0.85 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2NPC1CASP3RAB9A | |
| SCHEMBL10920698 | 0.84 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2NPC1CASP3RAB9A | |
| SCHEMBL25219122 | 0.84 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2NPC1CASP3RAB9A | |
| SCHEMBL30447202 | 0.84 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2NPC1CASP3RAB9A | |
| SCHEMBL31357336 | 0.83 | PTGS1 (0.59) | ALDH1A1SMN1; SMN2PTGS1MAPTCXCR1 | |
| SCHEMBL3519007 | 0.83 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2NPC1CASP3RAB9A | |
| SCHEMBL694483 | 0.83 | PTGS1 (0.59) | ALDH1A1SMN1; SMN2PTGS1MAPTCXCR1 | |
| SCHEMBL20669549 | 0.83 | PTGS1 (0.59) | ALDH1A1SMN1; SMN2PTGS1MAPTCXCR1 | |
| SCHEMBL11803372 | 0.83 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2NPC1CASP3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041442-A | Antiulcer agents | SYNTEX (U.S.A.) INC. (US) | 1991-08-20 | — | — | US | disclosed |