Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 5/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9772968 | 1.00 | ADRB3 (0.63) | ADRB3CYP2D6MEN1SLC22A1KMT2A | |
| Hydrochloric Acid SCHEMBL9772999 | 0.99 | ADRB3 (0.62) | ADRB3CYP2D6MEN1SLC22A1KMT2A | |
| Hydrochloric Acid SCHEMBL9773018 | 0.99 | ADRB3 (0.62) | ADRB3CYP2D6MEN1SLC22A1KMT2A | |
| SCHEMBL9773082 | 0.85 | CYP2D6 (0.54) | ADRB3CYP2D6MEN1KMT2A | |
| SCHEMBL9773074 | 0.85 | CYP2D6 (0.54) | ADRB3CYP2D6MEN1KMT2A | |
| SCHEMBL9772965 | 0.84 | ADRB3 (0.67) | ADRB3CYP2D6MEN1SLC22A1KMT2A | |
| SCHEMBL9772988 | 0.84 | ADRB3 (0.67) | ADRB3CYP2D6MEN1SLC22A1KMT2A | |
| SCHEMBL9773022 | 0.84 | LTA4H (0.48) | ADRB3CYP2D6MEN1KMT2A | |
| SCHEMBL9772996 | 0.84 | LTA4H (0.48) | ADRB3CYP2D6MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9773056 | 0.84 | CYP2D6 (0.53) | ADRB3CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030640-A | Alpha-heterocyclic ethanolamino alkylindoles, growth promoters and feed efficiency agents for animals, bronchodilators, antidepressants, antiobesity agents | MERCK & CO., INC. (US) | 1991-07-09 | — | — | US | claimed |
| US-5030640-A | Alpha-heterocyclic ethanolamino alkylindoles, growth promoters and feed efficiency agents for animals, bronchodilators, antidepressants, antiobesity agents | MERCK & CO., INC. (US) | 1991-07-09 | — | — | US | disclosed |