Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346034 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL12990296 | 0.85 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL27323312 | 0.83 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL27974233 | 0.83 | MEN1 (0.47) | ALDH1A1MAPK1L3MBTL1KMT2ASLC6A3 | |
| SCHEMBL27974234 | 0.83 | MEN1 (0.47) | ALDH1A1MAPK1L3MBTL1KMT2ASLC6A3 | |
| SCHEMBL17726803 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL8327125 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL8989009 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL8734619 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL2512047 | 0.82 | CYP3A4 (0.49) | ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043346-A | Amino acid esters, pharmaceuticals containing them, and the use thereof in learning disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-27 | — | — | US | disclosed |