Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9773993 | 1.00 | SPHK1 (0.46) | SPHK1SPHK2HDAC2MAOAMAOB | |
| SCHEMBL9773969 | 1.00 | SPHK1 (0.46) | SPHK1SPHK2HDAC2MAOAMAOB | |
| SCHEMBL9773985 | 1.00 | SPHK1 (0.46) | SPHK1SPHK2HDAC2MAOAMAOB | |
| SCHEMBL9182052 | 0.96 | SPHK1 (0.43) | SPHK1SPHK2HDAC2 | |
| SCHEMBL9182057 | 0.96 | SPHK1 (0.43) | SPHK1SPHK2HDAC2 | |
| SCHEMBL9166374 | 0.96 | SPHK1 (0.43) | SPHK1SPHK2HDAC2 | |
| SCHEMBL8454870 | 0.90 | SPHK1 (0.43) | SPHK1SPHK2HDAC2MAOAMAOB | |
| SCHEMBL8454866 | 0.90 | SPHK1 (0.43) | SPHK1SPHK2HDAC2MAOAMAOB | |
| SCHEMBL8454873 | 0.90 | SPHK1 (0.43) | SPHK1SPHK2HDAC2MAOAMAOB | |
| SCHEMBL9774253 | 0.89 | SPHK1 (0.40) | SPHK1SPHK2HDAC2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013478-A | Electromagnetic radiation resistance; miscibility; dielectrics; rotation and guest/host cells | HOFFMANN-LA ROCHE INC. (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0122389-B1 | LIQUID CRYSTAL COMPONENTS HAVING AN ALKENYL CHAIN | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-08-05 | — | — | EP | disclosed |
| US-4676604-A | RADIATION RESISTANCE; MISCIBILITY; ROTATION ELECTROPTICAL CELLS | HOFFMANN-LA ROCHE INC. (US) | 1987-06-30 | — | — | US | disclosed |
| US-4565425-A | Liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1986-01-21 | — | — | US | disclosed |
| EP-0122389-A2 | Liquid crystal components having an alkenyl chain | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-10-24 | — | — | EP | disclosed |