Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA7 | P43166 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.62 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | DPP4 | P27487 | 1/20 | 0.57 |
| ▸ | TYR | P14679 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MIF | P14174 | 1/20 | 0.55 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.54 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9774045 | 1.00 | CA12 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31618785 | 0.88 | ALDH1A1 (0.69) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3366451 | 0.88 | ALDH1A1 (0.69) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3366448 | 0.88 | ALDH1A1 (0.69) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15960946 | 0.88 | ESR1 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31683004 | 0.88 | TTR (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18538452 | 0.87 | MAOB (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28139586 | 0.87 | MAOB (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18538461 | 0.87 | CA12 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3917285 | 0.86 | CA12 (0.60) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047430-A | Glutamate Receptor Inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0339927-A2 | Amide compounds their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-11-02 | — | — | EP | disclosed |