Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9774314 | 0.98 | PREP (0.49) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL9774292 | 0.91 | PREP (0.45) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL9774157 | 0.88 | PREP (0.49) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL9774318 | 0.87 | PREP (0.51) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL10516071 | 0.87 | PREP (0.42) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL9774313 | 0.86 | MEN1 (0.50) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL10513313 | 0.85 | HRH1 (0.44) | PREP | |
| SCHEMBL9774332 | 0.84 | MEN1 (0.53) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL10516043 | 0.84 | FKBP1A (0.46) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL8153242 | 0.83 | MEN1 (0.55) | PREPMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983623-A | Prolyl endopeptidase inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-08 | — | — | US | disclosed |