SCHEMBL977444

SCHEMBL977444

C=C(C)C(=O)OCC(C)(C)CC[Si](C)(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
ALDH1A1 P00352 2/20 0.37
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL975026 0.87 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL15337 0.78 TSHR (0.50) TSHRALDH1A1THRB
SCHEMBL23494248 0.78 TSHR (0.47) TSHRALDH1A1THRB
SCHEMBL8966019 0.78 THRB (0.48) TSHRALDH1A1THRB
SCHEMBL65596 0.75 THRB (0.50) TSHRALDH1A1THRB
SCHEMBL3174059 0.75
SCHEMBL13657469 0.75 TSHR (0.53) TSHRALDH1A1THRB
SCHEMBL8965825 0.75 TSHR (0.53) TSHRALDH1A1THRB
SCHEMBL20998297 0.73 TSHR (0.47) TSHRALDH1A1THRB
SCHEMBL9576258 0.73 THRB (0.47) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101405315-B Moisture-curing compositions containing silane-functional polymers with good adhesive properties SIKA TECHNOLOGY AG 2011-04-13 CN disclosed
US-7867619-B2 Moisture-curing compositions containing silane-functional polymers with good adhesive properties SIKA TECHNOLOGY AG (CH) 2011-01-11 US disclosed
EP-1981924-B1 MOISTURE-CURING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS WITH GOOD ADHESIVE PROPERTIES SIKA TECHNOLOGY AG (CH) 2010-03-31 EP disclosed
US-20090214879-A1 Moisture-Curing Compositions Containing Silane-Functional Polymers With Good Adhesive Properties SIKA TECHNOLOGY AG (CH) 2009-08-27 US disclosed
CN-101405315-A Moisture-curing compositions containing silane-functional polymers with good adhesive properties SIKA TECHNOLOGY AG (CH) 2009-04-08 CN disclosed
EP-1981924-A1 MOISTURE-CURING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS WITH GOOD ADHESIVE PROPERTIES Sika Technology AG (CH) 2008-10-22 EP disclosed
WO-2007085620-A1 MOISTURE-CURING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS WITH GOOD ADHESIVE PROPERTIES SIKA TECHNOLOGY AG (CH) 2007-08-02 WO disclosed