SCHEMBL977446

SCHEMBL977446

C=C(C)C(=O)OCC(C)(C)CCC[SiH](OC)OC

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 2/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13657469 0.79 TSHR (0.53) TSHRPOLBAPEX1HTTTDP1
SCHEMBL8965825 0.79 TSHR (0.53) TSHRPOLBAPEX1HTTTDP1
SCHEMBL136943 0.77 TSHR (0.55) TSHRPOLBAPEX1HTTTDP1
SCHEMBL13651135 0.76 TSHR (0.50) TSHRPOLBAPEX1HTTTDP1
SCHEMBL28203708 0.76 TSHR (0.59) TSHRTDP1ALDH1A1THRB
SCHEMBL28769246 0.76 TSHR (0.59) TSHRTDP1ALDH1A1THRB
SCHEMBL15337 0.76 TSHR (0.50) TSHRPOLBAPEX1HTTTDP1
SCHEMBL35127 0.76 TSHR (0.58) TSHRPOLBAPEX1HTTTDP1
SCHEMBL23494248 0.75 TSHR (0.47) TSHRPOLBAPEX1HTTTDP1
SCHEMBL8966019 0.75 THRB (0.48) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7867619-B2 Moisture-curing compositions containing silane-functional polymers with good adhesive properties SIKA TECHNOLOGY AG (CH) 2011-01-11 US disclosed
US-20090214879-A1 Moisture-Curing Compositions Containing Silane-Functional Polymers With Good Adhesive Properties SIKA TECHNOLOGY AG (CH) 2009-08-27 US disclosed