Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11427031 | 0.82 | PSEN1 (0.41) | IDO1CARM1PRMT6HRH3 | |
| SCHEMBL9775057 | 0.81 | IDO1 (0.47) | IDO1CARM1PRMT6MAOBMAOA | |
| SCHEMBL10654122 | 0.81 | PTAFR (0.37) | — | |
| SCHEMBL18616297 | 0.74 | CARM1 (0.55) | IDO1CARM1PRMT6APPEPHX2 | |
| SCHEMBL2126154 | 0.72 | PSEN1 (0.39) | CARM1PRMT6LMNAALDH1A1HRH3 | |
| SCHEMBL15748046 | 0.70 | CTSL (0.40) | ALDH1A1 | |
| SCHEMBL19432863 | 0.67 | KMT2A (0.46) | EPHX2ALDH1A1RXRARXRBRAB9A | |
| SCHEMBL21602750 | 0.67 | HDAC1 (0.35) | ALDH1A1MAPTRAB9AHRH3 | |
| SCHEMBL10654118 | 0.67 | — | — | |
| SCHEMBL6436291 | 0.67 | CARM1 (0.51) | IDO1CARM1PRMT6APPEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327492-A1 | Herbicidally and plantgrowth regulatory active quinoline and pyrindine compounds | CIBA-GEIGY AG (CH) | 1989-08-09 | — | — | EP | claimed |
| US-5039673-A | Anticoagulants, bronchodilators, vasodilators | GLAXO GROUP LIMITED (GB) | 1991-08-13 | — | — | US | disclosed |
| EP-0337739-A2 | Use of TP-receptor antagonists to modify the action of myofibroblasts | GLAXO GROUP LIMITED (GB) | 1989-10-18 | — | — | EP | disclosed |
| EP-0327492-A1 | Herbicidally and plantgrowth regulatory active quinoline and pyrindine compounds | CIBA-GEIGY AG (CH) | 1989-08-09 | — | — | EP | disclosed |
| EP-0296802-A1 | Aminocyclopentyl ethers and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1988-12-28 | — | — | EP | disclosed |