SCHEMBL977529

SCHEMBL977529

CC=CC(=O)OCC(C)C[Si](C)(OC)OC

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
GSTP1 P09211 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9301363 0.85 TSHR (0.37) TSHRGSTP1
SCHEMBL975410 0.85 TSHR (0.35) TSHRGSTP1
SCHEMBL2772661 0.84 HCAR2 (0.33) TSHRGSTP1
SCHEMBL9302383 0.79 TSHR (0.33) TSHRGSTP1
SCHEMBL9301566 0.79 TSHR (0.33) TSHRGSTP1
SCHEMBL1468238 0.77 GSTP1 (0.35) GSTP1
SCHEMBL27293911 0.77 TSHR (0.39) TSHRGSTP1
SCHEMBL4751406 0.76
SCHEMBL1330616 0.75 HCAR2 (0.34) TSHRGSTP1
SCHEMBL1532470 0.74 TSHR (0.59) TSHRGSTP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7867619-B2 Moisture-curing compositions containing silane-functional polymers with good adhesive properties SIKA TECHNOLOGY AG (CH) 2011-01-11 US disclosed
US-7851562-B2 Water-soluble silicon-containing polymer, making method, coating composition, and coated article SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-12-14 US disclosed
EP-1925627-B1 Water-soluble silicon-containing polymer, making method, coating composition, and coated article SHINETSU CHEMICAL CO (JP) 2010-04-28 EP disclosed
EP-1981924-B1 MOISTURE-CURING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS WITH GOOD ADHESIVE PROPERTIES SIKA TECHNOLOGY AG (CH) 2010-03-31 EP disclosed
US-20090214879-A1 Moisture-Curing Compositions Containing Silane-Functional Polymers With Good Adhesive Properties SIKA TECHNOLOGY AG (CH) 2009-08-27 US disclosed
EP-1981924-A1 MOISTURE-CURING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS WITH GOOD ADHESIVE PROPERTIES Sika Technology AG (CH) 2008-10-22 EP disclosed
US-20080132652-A1 WATER-SOLUBLE SILICON-CONTAINING POLYMER, MAKING METHOD, COATING COMPOSITION, AND COATED ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-06-05 US disclosed
EP-1925627-A1 Water-soluble silicon-containing polymer, making method, coating composition, and coated article Shin-Etsu Chemical Co., Ltd. (JP) 2008-05-28 EP disclosed
WO-2007085620-A1 MOISTURE-CURING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS WITH GOOD ADHESIVE PROPERTIES SIKA TECHNOLOGY AG (CH) 2007-08-02 WO disclosed