SCHEMBL975410

SCHEMBL975410

CC=CC(=O)OCC(C)C[Si](OC)(OC)OC

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
GSTP1 P09211 1/20 0.32
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4751406 0.87
SCHEMBL977529 0.85 TSHR (0.34) TSHRGSTP1
SCHEMBL1330616 0.83 HCAR2 (0.34) TSHRGSTP1
SCHEMBL9301566 0.83 TSHR (0.33) TSHRGSTP1
SCHEMBL4252481 0.81 TSHR (0.58) TSHRALDH1A1HPGD
SCHEMBL27293911 0.78 TSHR (0.39) TSHRGSTP1ALDH1A1HPGD
SCHEMBL9301363 0.77 TSHR (0.37) TSHRGSTP1
SCHEMBL9302383 0.77 TSHR (0.33) TSHRGSTP1
SCHEMBL4751102 0.76
SCHEMBL2671273 0.76 GSTP1 (0.36) GSTP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1799750-B1 POLYETHER-FUNCTIONAL SILOXANES, POLYETHER SILOXANE-CONTAINING COMPOSITIONS, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2014-09-17 EP claimed
US-8236918-B2 Polyether-functional siloxanes, polyether siloxane-containing compositions, methods for the production thereof and use thereof EVONIK DEGUSSA GMBH (DE) 2012-08-07 US claimed
US-8043701-B2 Polymerizable organosilicon nanocapsules EVONIK DEGUSSA GMBH (DE) 2011-10-25 US claimed
US-20090030162-A1 Polyether-Functional Siloxanes, Polyether Siloxane-Containing Compositions, Methods For The Production Thereof And Use Thereof DEGUSSA GMBH (DE) 2009-01-29 US claimed
US-20080283972-A1 Silicon Compounds for Producing Sio2-Containing Insulating Layers on Chips DEGUSSA AG (DE) 2008-11-20 US claimed
EP-1245627-B1 Organic silicon nano-microhybrid system or micro-hybrid system containing compositions for scratch and abrasion resistant coatings DEGUSSA (DE) 2007-07-04 EP claimed
EP-1799750-A1 POLYETHER-FUNCTIONAL SILOXANES, POLYETHER SILOXANE-CONTAINING COMPOSITIONS, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF Degussa GmbH (DE) 2007-06-27 EP claimed
EP-1716269-A2 PROCESS FOR PRODUCING SIO2-CONTAINING INSULATING LAYERS ON CHIPS Degussa GmbH (DE) 2006-11-02 EP claimed
WO-2006037380-A1 POLYETHER-FUNCTIONAL SILOXANES, POLYETHER SILOXANE-CONTAINING COMPOSITIONS, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF DEGUSSA GMBH (DE) 2006-04-13 WO claimed
US-20060063002-A1 Polymerizable organosilicon nanocapsules DEGUSSA AG (DE) 2006-03-23 US claimed
WO-2005080629-A2 SILICON COMPOUNDS FOR PRODUCING SiO2-CONTAINING INSULATING LAYERS ON CHIPS DEGUSSA AG (DE) 2005-09-01 WO claimed
US-6830816-B2 For preparing lacquer DEGUSSA AG (DE) 2004-12-14 US claimed
US-6699586-B2 Organosilicon nano/microhybrid or microhybrid system composition for scratch and abrasion resistant coatings DEGUSSA AG (DE) 2004-03-02 US claimed
US-20030008974-A1 Highly filled, pasty, composition containing silicoorganic nanohybrid and/or microhybrid capsules for scratch-resistant and/or abrasion-resistant coatings DEGUSSA AG (DE) 2003-01-09 US claimed
US-20020197475-A1 Organosilicon nano/microhybrid or microhybrid system composition for scratch and abrasion resistant coatings DEGUSSA AG (DE) 2002-12-26 US claimed
EP-1249470-A2 Highly filled pasty siliconorganic nano and/or microhybridcapsules containing composition for scratch and/or abrasion resistant coatings Degussa AG (DE) 2002-10-16 EP claimed
EP-1245627-A2 Organic silicon nano-microhybrid system or micro-hybrid system containing compositions for scratch and abrasion resistant coatings Degussa AG (DE) 2002-10-02 EP claimed
US-20020098243-A1 For use in scratch resistant coatings for automobiles; comprises organosilicon compound/polymer shell and metal oxide core which are covalently attached DEGUSSA AG (DE) 2002-07-25 US claimed
EP-1195416-A2 Polymerisable silicone-organic nanocapsules Degussa AG (DE) 2002-04-10 EP claimed
US-20230357081-A1 Non-Combustible Cement Board BANK OF AMERICA, N.A., AS COLLATERAL AGENT 2023-11-09 US disclosed
US-11560635-B2 Electrode for gas generation, method of preparing the electrode and device including the electrode for gas generation UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY) (KR) 2023-01-24 US disclosed
US-20220411330-A1 GYPSUM BOARD INCLUDING A COATED FACING MATERIAL BANK OF AMERICA, N.A., AS COLLATERAL AGENT 2022-12-29 US disclosed
US-20200325586-A1 Electrode for Gas Generation, Method of Preparing the Electrode and Device Including the Electrode for Gas Generation UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY) (KR) 2020-10-15 US disclosed
EP-1843991-B1 AQUEOUS EMULSIONS OF FUNCTIONAL ALKOXYSILANES AND CONDENSED OLIGOMERS THEREOF, THEIR PREPARATION AND USE FOR SURFACE TREATMENT EVONIK DEGUSSA GMBH (DE) 2015-09-02 EP disclosed
EP-1799750-B1 POLYETHER-FUNCTIONAL SILOXANES, POLYETHER SILOXANE-CONTAINING COMPOSITIONS, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2014-09-17 EP disclosed
US-8795784-B2 Aqueous emulsions of functional alkoxysilanes and condensed oligomers thereof, their preparation and use for surface treatment EVONIK DEGUSSA GMBH (DE) 2014-08-05 US disclosed
US-8431646-B2 Mixture containing organosilicon compound and use thereof EVONIK DEGUSSA GMBH (DE) 2013-04-30 US disclosed
EP-1844120-B1 HIGH-VISCOSITY AQUEOUS EMULSIONS OF FUNCTIONAL ALKOXYSILANES, CONDENSED OLIGOMERS THEREOF, ORGANOPOLYSILOXANES, THEIR PREPARATION AND USE FOR SURFACE TREATMENT OF INORGANIC MATERIALS EVONIK DEGUSSA GMBH (DE) 2012-10-24 EP disclosed
US-8236918-B2 Polyether-functional siloxanes, polyether siloxane-containing compositions, methods for the production thereof and use thereof EVONIK DEGUSSA GMBH (DE) 2012-08-07 US disclosed
WO-2012084404-A1 COMPOSITION HAVING IMPROVED WEATHERING STABILITY OF THE COLOUR OF BUILDING MATERIALS AND PROCESS FOR THE PRODUCTION THEREOF EVONIK DEGUSSA GMBH (DE) 2012-06-28 WO disclosed
US-20110282024-A1 CATALYSTS FOR THE CROSS-LINKING OF FUNCTIONAL SILANES OR FUNCTIONAL SILOXANES, PARTICULARLY WITH SUBSTRATES EVONIK DEGUSSA GMBH (DE) 2011-11-17 US disclosed
EP-2331622-A1 NEW CATALYSTS FOR THE CROSS-LINKING OF FUNCTIONAL SILANES OR FUNCTIONAL SILOXANES, PARTICULARLY WITH SUBSTRATES Evonik Degussa GmbH (DE) 2011-06-15 EP disclosed
US-7867619-B2 Moisture-curing compositions containing silane-functional polymers with good adhesive properties SIKA TECHNOLOGY AG (CH) 2011-01-11 US disclosed
US-7851562-B2 Water-soluble silicon-containing polymer, making method, coating composition, and coated article SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-12-14 US disclosed
US-7781520-B2 High-viscosity aqueous emulsions of functional alkoxysilanes, condensed oligomers thereof, organopolysiloxanes, their preparation and use for surface treatment of inorganic materials EVONIK DEGUSSA GMBH (DE) 2010-08-24 US disclosed
US-20100119851-A1 MIXTURE CONTAINING ORGANOSILICON COMPOUND AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2010-05-13 US disclosed
EP-1925627-B1 Water-soluble silicon-containing polymer, making method, coating composition, and coated article SHINETSU CHEMICAL CO (JP) 2010-04-28 EP disclosed
EP-1981924-B1 MOISTURE-CURING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS WITH GOOD ADHESIVE PROPERTIES SIKA TECHNOLOGY AG (CH) 2010-03-31 EP disclosed
WO-2010028877-A1 NEW CATALYSTS FOR THE CROSS-LINKING OF FUNCTIONAL SILANES OR FUNCTIONAL SILOXANES, PARTICULARLY WITH SUBSTRATES EVONIK DEGUSSA GMBH (DE) 2010-03-18 WO disclosed
US-20090214879-A1 Moisture-Curing Compositions Containing Silane-Functional Polymers With Good Adhesive Properties SIKA TECHNOLOGY AG (CH) 2009-08-27 US disclosed
US-20090030162-A1 Polyether-Functional Siloxanes, Polyether Siloxane-Containing Compositions, Methods For The Production Thereof And Use Thereof DEGUSSA GMBH (DE) 2009-01-29 US disclosed
US-20080283972-A1 Silicon Compounds for Producing Sio2-Containing Insulating Layers on Chips DEGUSSA AG (DE) 2008-11-20 US disclosed
WO-2008128819-A1 MIXTURE CONTAINING ORGANOSILICON COMPOUND AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2008-10-30 WO disclosed
EP-1981924-A1 MOISTURE-CURING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS WITH GOOD ADHESIVE PROPERTIES Sika Technology AG (CH) 2008-10-22 EP disclosed
EP-1982964-A1 Preparation containing organosilicium compound and its use Evonik Degussa GmbH (DE) 2008-10-22 EP disclosed
US-20080188617-A1 High-Viscosity Aqueous Emulsions Of Functional Alkoxysilanes, Condensed Oligomers Thereof, Organopolysiloxanes, Their Preparation And Use For Surface Treatment Of Inorganic Materials DEGUSSA GMBH (DE) 2008-08-07 US disclosed
US-20080187673-A1 Oil in water emulsions; aqueous solution containing emulsifiers; controlling particle size of drops DEGUSSA GMBH (DE) 2008-08-07 US disclosed
US-20080132652-A1 WATER-SOLUBLE SILICON-CONTAINING POLYMER, MAKING METHOD, COATING COMPOSITION, AND COATED ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-06-05 US disclosed
EP-1925627-A1 Water-soluble silicon-containing polymer, making method, coating composition, and coated article Shin-Etsu Chemical Co., Ltd. (JP) 2008-05-28 EP disclosed
EP-1843991-A1 AQUEOUS EMULSIONS OF FUNCTIONAL ALKOXYSILANES AND CONDENSED OLIGOMERS THEREOF, THEIR PREPARATION AND USE FOR SURFACE TREATMENT Degussa GmbH (DE) 2007-10-17 EP disclosed
EP-1844120-A1 HIGH-VISCOSITY AQUEOUS EMULSIONS OF FUNCTIONAL ALKOXYSILANES, CONDENSED OLIGOMERS THEREOF, ORGANOPOLYSILOXANES, THEIR PREPARATION AND USE FOR SURFACE TREATMENT OF INORGANIC MATERIALS Degussa GmbH (DE) 2007-10-17 EP disclosed
US-20070202267-A1 Sizing compositions for glass and polyolefin surfaces and methods of use MARTIN EMIL 2007-08-30 US disclosed
WO-2007085620-A1 MOISTURE-CURING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS WITH GOOD ADHESIVE PROPERTIES SIKA TECHNOLOGY AG (CH) 2007-08-02 WO disclosed
EP-1799750-A1 POLYETHER-FUNCTIONAL SILOXANES, POLYETHER SILOXANE-CONTAINING COMPOSITIONS, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF Degussa GmbH (DE) 2007-06-27 EP disclosed
EP-1716269-A2 PROCESS FOR PRODUCING SIO2-CONTAINING INSULATING LAYERS ON CHIPS Degussa GmbH (DE) 2006-11-02 EP disclosed
WO-2006081891-A1 HIGH-VISCOSITY AQUEOUS EMULSIONS OF FUNCTIONAL ALKOXYSILANES, CONDENSED OLIGOMERS THEREOF, ORGANOPOLYSILOXANES, THEIR PREPARATION AND USE FOR SURFACE TREATMENT OF INORGANIC MATERIALS DEGUSSA GMBH (DE) 2006-08-10 WO disclosed
WO-2006081892-A1 AQUEOUS EMULSIONS OF FUNCTIONAL ALKOXYSILANES AND CONDENSED OLIGOMERS THEREOF, THEIR PREPARATION AND USE FOR SURFACE TREATMENT DEGUSSA GMBH (DE) 2006-08-10 WO disclosed
EP-1205481-B1 N-Propylethoxysiloxane, preparation and use thereof DEGUSSA (DE) 2006-05-31 EP disclosed
WO-2006037380-A1 POLYETHER-FUNCTIONAL SILOXANES, POLYETHER SILOXANE-CONTAINING COMPOSITIONS, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF DEGUSSA GMBH (DE) 2006-04-13 WO disclosed
WO-2005080629-A2 SILICON COMPOUNDS FOR PRODUCING SiO2-CONTAINING INSULATING LAYERS ON CHIPS DEGUSSA AG (DE) 2005-09-01 WO disclosed
US-6841197-B2 For use in hydrophobicization of absorbent mineral materials, surface treatment to have surafaces repelling water, oil or dirt or preventing bioinfestation and/or corrosion of inorganic surfaces DEGUSSA AG (DE) 2005-01-11 US disclosed
US-6830816-B2 For preparing lacquer DEGUSSA AG (DE) 2004-12-14 US disclosed
US-6699586-B2 Organosilicon nano/microhybrid or microhybrid system composition for scratch and abrasion resistant coatings DEGUSSA AG (DE) 2004-03-02 US disclosed
US-20030008974-A1 Highly filled, pasty, composition containing silicoorganic nanohybrid and/or microhybrid capsules for scratch-resistant and/or abrasion-resistant coatings DEGUSSA AG (DE) 2003-01-09 US disclosed
US-20020197475-A1 Organosilicon nano/microhybrid or microhybrid system composition for scratch and abrasion resistant coatings DEGUSSA AG (DE) 2002-12-26 US disclosed
EP-1249470-A2 Highly filled pasty siliconorganic nano and/or microhybridcapsules containing composition for scratch and/or abrasion resistant coatings Degussa AG (DE) 2002-10-16 EP disclosed
EP-1245627-A2 Organic silicon nano-microhybrid system or micro-hybrid system containing compositions for scratch and abrasion resistant coatings Degussa AG (DE) 2002-10-02 EP disclosed
US-20020090316-A1 For use in hydrophobicization of absorbent mineral materials, surface treatment to have surafaces repelling water, oil or dirt or preventing bioinfestation and/or corrosion of inorganic surfaces DEGUSSA AG (DE) 2002-07-11 US disclosed
EP-1205481-A2 N-Propylethoxysiloxane, preparation and use Degussa AG (DE) 2002-05-15 EP disclosed
EP-1205481-A2 N-Propylethoxysiloxane, preparation and use Degussa AG (DE) 2002-05-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110282024-A1 CATALYSTS FOR THE CROSS-LINKING OF FUNCTIONAL SILANES OR FUNCTIONAL SILOXANES, PARTICULARLY WITH SUBSTRATES SI, FOXO1, F11 TSHR 3535/4885GSTP1 1888/4885ALDH1A1 1694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.