SCHEMBL9775426

SCHEMBL9775426

CC[Si](CC)(CCCl)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
TP53 P04637 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL988676 0.83 NR1H2 (0.43) NR1H2NR1H3TP53KDM4EESR1
SCHEMBL27924051 0.82 NR1H2 (0.42) NR1H2NR1H3TP53KDM4EESR1
SCHEMBL9775411 0.78 TDP1 (0.34) NR1H2NR1H3TP53ESR1ESR2
SCHEMBL10419091 0.78 ALDH1A1 (0.36) NR1H2NR1H3TP53ESR1ESR2
SCHEMBL20637391 0.77 NR1H2 (0.42) NR1H2NR1H3TP53KDM4EESR1
SCHEMBL28627134 0.75 NR1H2 (0.42) NR1H2NR1H3TP53ESR1ESR2
SCHEMBL8684348 0.74 HDAC3 (0.37) NR1H2NR1H3
SCHEMBL28113996 0.73 NR1H2 (0.36) NR1H2NR1H3TP53ESR1ESR2
SCHEMBL28024246 0.73 MAPT (0.41) NR1H2NR1H3ESR1ESR2
SCHEMBL8543839 0.73 NR1H2 (0.36) NR1H2NR1H3TP53ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5027157-A Developing device provided with electrodes for inducing a traveling wave on the developing material MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1991-06-25 US disclosed
US-4971880-A MULTILAYER TONERS, DEVELOPERS, FOR ELECTROSTATIC LATENT IMAGES, CORES AND HALOGENATED CARBON PARTICLES MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1990-11-20 US disclosed
US-4867541-A FILM FORMED BY PLASMA POLYMERIZATION OF PHTHALOCYANINE COMPOUND MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1989-09-19 US disclosed
US-4828369-A ELECTROLYTES, PLASMA POLYMERIZATION OF HYDROCARBON, ALKALI METAL /COMPOUND/, ELECTRONEGATIVITY MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1989-05-09 US disclosed
US-4801515-A Photosensitive member having an overcoat layer MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1989-01-31 US disclosed
EP-0252442-A2 Photosensitive member having an overcoat layer Minolta Camera Kabushiki Kaisha (JP) 1988-01-13 EP disclosed