SCHEMBL9775466

SCHEMBL9775466

CN(C)c1ccc(C=NN(c2ccccc2)c2ccc3ccccc3c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.51
KMT2A Q03164 6/20 0.51
SMN1; SMN2 Q16637 5/20 0.51
MEN1 O00255 4/20 0.51
MCL1 Q07820 2/20 0.51
G6PC1 P35575 1/20 0.50
KDM4E B2RXH2 3/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
GLA P06280 1/20 0.49
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
RRM1 P23921 1/20 0.44
RELA Q04206 1/20 0.44
MAPT P10636 4/20 0.43
RAB9A P51151 4/20 0.43
TP53 P04637 2/20 0.43
HSD17B10 Q99714 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL331931 0.88 ALDH1A1 (0.62) ALDH1A1KMT2ASMN1; SMN2MEN1MCL1
SCHEMBL331930 0.88 ALDH1A1 (0.62) ALDH1A1KMT2ASMN1; SMN2MEN1MCL1
SCHEMBL9915795 0.86 CYP1A2 (0.45) ALDH1A1KMT2ASMN1; SMN2MEN1MCL1
SCHEMBL11938809 0.86 CYP1A2 (0.45) ALDH1A1KMT2ASMN1; SMN2MEN1MCL1
SCHEMBL9238587 0.85 MAPT (0.54) ALDH1A1KMT2ASMN1; SMN2MEN1MCL1
SCHEMBL12677641 0.85 MEN1 (0.43) ALDH1A1KMT2ASMN1; SMN2MEN1MCL1
SCHEMBL9775483 0.81 KMT2A (0.47) ALDH1A1KMT2ASMN1; SMN2MEN1MCL1
SCHEMBL12637395 0.78 SMN1; SMN2 (0.53) ALDH1A1KMT2ASMN1; SMN2MEN1MCL1
SCHEMBL9775459 0.78 ALDH1A1 (0.49) ALDH1A1KMT2ASMN1; SMN2MEN1MCL1
SCHEMBL9775460 0.78 ALDH1A1 (0.49) ALDH1A1KMT2ASMN1; SMN2MEN1MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4990625-A Process for synthesis of N,N-disubstituted hydrazone CANON KABUSHIKI KAISHA (JP) 1991-02-05 US disclosed