Dimethylamine

Dimethylamine

SCHEMBL9775470

CNC.O=Cc1ccccc1Cl

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
LMNA P02545 1/20 0.52
THRB P10828 1/20 0.52
BLM P54132 1/20 0.52
ALDH1A1 P00352 3/20 0.48
TSHR P16473 1/20 0.48
HDAC1 Q13547 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
NFE2L2 Q16236 2/20 0.43
RELA Q04206 1/20 0.43
TRIM24 O15164 1/20 0.43
TRIM33 Q9UPN9 1/20 0.43
MAOB P27338 2/20 0.41
NPC1 O15118 1/20 0.41
MAPT P10636 1/20 0.41
RAB9A P51151 1/20 0.41
CHAT P28329 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethane SCHEMBL2154274 0.91 TDP1 (0.57) TDP1MEN1KMT2ALMNATHRB
SCHEMBL1509673 0.91 TDP1 (0.63) TDP1MEN1KMT2ALMNATHRB
SCHEMBL29815450 0.91
SCHEMBL97422 0.91
Methyl Alcohol SCHEMBL28778721 0.88 TDP1 (0.55) TDP1MEN1KMT2ALMNATHRB
SCHEMBL29924187 0.88 TDP1 (0.60) TDP1MEN1KMT2ALMNATHRB
SCHEMBL29684596 0.88 TDP1 (0.60) TDP1MEN1KMT2ALMNATHRB
Hydrochloric Acid SCHEMBL10816378 0.88 TDP1 (0.60) TDP1MEN1KMT2ALMNATHRB
Methane SCHEMBL10926734 0.88 TDP1 (0.60) TDP1MEN1KMT2ALMNATHRB
Phosphine SCHEMBL27593892 0.88 TDP1 (0.60) TDP1MEN1KMT2ALMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4990625-A Process for synthesis of N,N-disubstituted hydrazone CANON KABUSHIKI KAISHA (JP) 1991-02-05 US disclosed