Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775453 | 1.00 | BRD4 (0.39) | BRD4TSHRSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL9515884 | 0.89 | BRD4 (0.37) | BRD4TSHRSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL9518225 | 0.89 | BRD4 (0.37) | BRD4TSHRSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL9775490 | 0.89 | BRD4 (0.37) | BRD4TSHRSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL9775451 | 0.89 | BRD4 (0.37) | BRD4TSHRSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL9021385 | 0.76 | KDM4E (0.35) | TSHRSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL9269310 | 0.76 | KDM4E (0.35) | TSHRSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL8369583 | 0.71 | BRD4 (0.41) | BRD4TSHREDNRAPOLBKDM4E | |
| SCHEMBL8954733 | 0.71 | BRD4 (0.41) | BRD4TSHREDNRAPOLBKDM4E | |
| SCHEMBL8954782 | 0.71 | BRD4 (0.41) | BRD4TSHREDNRAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077303-A | OXIRANE PHENYL ESTERS AND FUNGICIDES CONTAINING THESE | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-31 | — | — | US | disclosed |