Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11666684 | 0.88 | ALDH1A1 (0.64) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL11751428 | 0.84 | SMN1; SMN2 (0.62) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL11751434 | 0.83 | ALDH1A1 (0.61) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL4070292 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL4593201 | 0.80 | ALDH1A1 (0.76) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL1965857 | 0.78 | ALDH1A1 (0.78) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL31091353 | 0.78 | ALDH1A1 (0.61) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9271967 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8365211 | 0.76 | TSHR (0.66) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL2720141 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987140-A | ANTIINFLAMMATORY, ANTIRHEUMATIC | ROUSSEL UCLAF (FR) | 1991-01-22 | — | — | US | disclosed |
| US-4925859-A | Novel 4-hydroxy-3-pyridine-carboxamides useful for treating inflammation and rheumatism | ROUSSEL UCLAF (FR) | 1990-05-15 | — | — | US | disclosed |