SCHEMBL9775631

SCHEMBL9775631

CCCCCCCCC(CCC)NS(=O)(=O)CC(=O)Nc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 11/20 0.51
HDAC3 O15379 9/20 0.51
HDAC6 Q9UBN7 9/20 0.51
HDAC1 Q13547 8/20 0.51
HDAC2 Q92769 8/20 0.51
HDAC4 P56524 5/20 0.50
HDAC7 Q8WUI4 5/20 0.50
HDAC10 Q969S8 5/20 0.50
HDAC11 Q96DB2 5/20 0.50
HDAC9 Q9UKV0 5/20 0.50
HDAC5 Q9UQL6 5/20 0.50
ENPP2 Q13822 1/20 0.47
ICMT O60725 1/20 0.47
ALB P02768 1/20 0.47
SOAT2 O75908 1/20 0.47
SOAT1 P35610 1/20 0.47
HSD17B10 Q99714 1/20 0.45
EPHX1 P07099 3/20 0.45
ALDH1A1 P00352 2/20 0.45
HTT P42858 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8164969 0.80 HDAC8 (0.53) HDAC8HDAC3HDAC6HDAC1HDAC2
SCHEMBL29134272 0.75 HDAC8 (0.71) HDAC8HDAC3HDAC6HDAC1HDAC2
SCHEMBL29828684 0.75 HDAC8 (0.71) HDAC8HDAC3HDAC6HDAC1HDAC2
SCHEMBL11526181 0.74 MMP2 (0.53) HDAC8HDAC3HDAC6HDAC1HDAC2
SCHEMBL22522223 0.73 HDAC8 (0.66) HDAC8HDAC3HDAC6HDAC1HDAC2
SCHEMBL8361856 0.72 HDAC8 (0.59) HDAC8HDAC3HDAC6HDAC1HDAC2
SCHEMBL28751121 0.72 HDAC8 (0.59) HDAC8HDAC3HDAC6HDAC1HDAC2
SCHEMBL11425047 0.72 HDAC8 (0.66) HDAC8HDAC3HDAC6HDAC1HDAC2
SCHEMBL8361871 0.72 HDAC8 (0.59) HDAC8HDAC3HDAC6HDAC1HDAC2
SCHEMBL28034004 0.72 SMN1; SMN2 (0.62) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4992360-A Silver halide light-sensitive photographic material containing a novel yellow coupler KONICA CORPORATION (JP) 1991-02-12 US disclosed
EP-0267491-A2 Silver halide light-sensitive photographic material containing a novel yellow coupler KONICA CORPORATION (JP) 1988-05-18 EP disclosed