Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27459942 | 0.92 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL31351330 | 0.85 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8943942 | 0.84 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29115530 | 0.83 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18916918 | 0.81 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL14044625 | 0.80 | THRB (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28066751 | 0.79 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27921818 | 0.79 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28176448 | 0.79 | THRB (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18953068 | 0.78 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999218-A | (Meth)acrylate copolymer and aromatic ketone dispersion; concrete roof tiles | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |