SCHEMBL9775783

SCHEMBL9775783

CCOC(C#CCBr)OCC

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16161130 0.81 THRB (0.32) THRBLMNA
SCHEMBL29156560 0.79 THRB (0.38) THRBLMNA
SCHEMBL16161156 0.78
SCHEMBL16161028 0.76
SCHEMBL8684636 0.75 THRB (0.35) THRBLMNA
SCHEMBL28392170 0.75 THRB (0.35) THRBLMNA
SCHEMBL16161231 0.74
SCHEMBL16161064 0.74
SCHEMBL16161217 0.74
SCHEMBL16161658 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0232851-B1 POLYSACCARIDE DERIVATIVES CONTAINING ALDEHYDE GROUPS, CORRESPONDING ACETALS AND USE AS PAPER ADDITIVES National Starch and Chemical Investment Holding Corporation (US) 1991-07-31 EP disclosed
US-4983748-A Chemical intermediates for polysaccharide aldehydes; wet strength paper additive NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1991-01-08 US disclosed
US-4804769-A PAPER ADDITIVES NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1989-02-14 US disclosed
US-4741804-A Polysaccharide derivatives containing aldehyde groups, their preparation from the corresponding acetals and use as paper additives NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1988-05-03 US disclosed
US-4703116-A WET STRENGTH, DRY STRENGTH NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1987-10-27 US disclosed
EP-0232851-A2 Polysaccaride derivatives containing aldehyde groups, corresponding acetals and use as paper additives National Starch and Chemical Investment Holding Corporation (US) 1987-08-19 EP disclosed