Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977578 | 1.00 | SLC9A3 (0.32) | SLC9A3AGTR2 | |
| SCHEMBL4898996 | 0.82 | SLC9A3 (0.36) | SLC9A3 | |
| SCHEMBL4914119 | 0.81 | SLC9A3 (0.35) | SLC9A3 | |
| SCHEMBL4898994 | 0.78 | NPC1 (0.35) | SLC9A3 | |
| SCHEMBL4899001 | 0.78 | NPC1 (0.35) | SLC9A3 | |
| SCHEMBL978855 | 0.78 | SLC9A3 (0.35) | SLC9A3 | |
| SCHEMBL4028962 | 0.77 | SLC9A3 (0.46) | SLC9A3 | |
| SCHEMBL978750 | 0.76 | SLC9A3 (0.39) | SLC9A3 | |
| SCHEMBL979823 | 0.76 | SLC9A3 (0.39) | SLC9A3 | |
| SCHEMBL12922732 | 0.74 | ALDH1A1 (0.32) | SLC9A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868003-B2 | Substituted 4-phenyltetrahydroisoquinolines, pharmaceutical compositions comprising them and therapeutic methods for their use | SANOFI-AVENTIS (FR) | 2011-01-11 | — | — | US | disclosed |