Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 5/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527026 | 0.89 | DRD3 (0.52) | ALDH1A1DRD3KDM4ELMNAKMT2A | |
| SCHEMBL9775905 | 0.89 | KDM4E (0.49) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9094359 | 0.86 | ALDH1A1 (0.55) | ALDH1A1DRD3KDM4ELMNAKMT2A | |
| SCHEMBL9526321 | 0.86 | ALDH1A1 (0.49) | ALDH1A1DRD3KDM4ELMNAKMT2A | |
| SCHEMBL9786221 | 0.85 | ALDH1A1 (0.47) | ALDH1A1DRD3KDM4ELMNAKMT2A | |
| Hydrochloric Acid SCHEMBL9097124 | 0.85 | ALDH1A1 (0.54) | ALDH1A1DRD3KDM4ELMNAKMT2A | |
| SCHEMBL9775874 | 0.85 | KMT2A (0.41) | ALDH1A1DRD3KDM4ELMNAKMT2A | |
| SCHEMBL8942000 | 0.85 | KMT2A (0.48) | ALDH1A1DRD3KDM4ELMNAKMT2A | |
| SCHEMBL7228568 | 0.84 | ALDH1A1 (0.45) | ALDH1A1DRD3KDM4ELMNAKMT2A | |
| Water SCHEMBL9776084 | 0.84 | KMT2A (0.40) | ALDH1A1DRD3KDM4ELMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004745-A | Benzo[1,8]naphthyridine derivatives, their preparation and the compositions which contain them | LABORATOIRE ROGER BELLON (FR) | 1991-04-02 | — | — | US | disclosed |
| US-4990515-A | Chemical intermediates | RHONE-POULENC SANTE (FR) | 1991-02-05 | — | — | US | disclosed |
| US-4970213-A | Benzo(1,8)naphthyridine derivatives as intermediates | RHONE-POULENC SANTE (FR) | 1990-11-13 | — | — | US | disclosed |