Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775899 | 0.98 | FPR3 (0.57) | FPR3KDM4ETP53ABCB1MEN1 | |
| SCHEMBL9776025 | 0.98 | FPR3 (0.57) | FPR3KDM4ETP53ABCB1MEN1 | |
| SCHEMBL9776162 | 0.86 | ABCB1 (0.51) | FPR3ABCB1MEN1KMT2AALDH1A1 | |
| SCHEMBL13783297 | 0.84 | ABCB1 (0.52) | FPR3KDM4ETP53ABCB1MEN1 | |
| SCHEMBL6326696 | 0.81 | MEN1 (0.58) | KDM4ETP53MEN1KMT2ATSHR | |
| SCHEMBL30151601 | 0.81 | MEN1 (0.58) | KDM4ETP53MEN1KMT2ATSHR | |
| SCHEMBL10412457 | 0.80 | MEN1 (0.56) | KDM4ETP53MEN1KMT2ATSHR | |
| SCHEMBL11607923 | 0.80 | MEN1 (0.56) | KDM4ETP53MEN1KMT2ATSHR | |
| SCHEMBL10413247 | 0.80 | MEN1 (0.56) | KDM4ETP53MEN1KMT2ATSHR | |
| SCHEMBL11605849 | 0.80 | MEN1 (0.56) | KDM4ETP53MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023254-A | Administering antiestrogens | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-06-11 | — | — | US | disclosed |
| US-4943572-A | 1-carbamoylalkyl-2-phenylindoles, pharmaceutical compositions and use | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-07-24 | — | — | US | disclosed |