Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9776298 | 0.93 | MAPT (0.49) | MAPTALDH1A1SMN1; SMN2POLBPKM | |
| SCHEMBL9776302 | 0.87 | MAPT (0.52) | MAPTALDH1A1SMN1; SMN2POLBPKM | |
| SCHEMBL18630658 | 0.85 | MAPT (0.60) | MAPTALDH1A1SMN1; SMN2POLBPKM | |
| SCHEMBL9776285 | 0.84 | MAPT (0.50) | MAPTALDH1A1POLBKMT2AKDM4E | |
| SCHEMBL9776267 | 0.84 | KMT2A (0.62) | MAPTALDH1A1SMN1; SMN2POLBPKM | |
| SCHEMBL9776275 | 0.83 | MAPT (0.40) | MAPTALDH1A1SMN1; SMN2POLBPKM | |
| SCHEMBL9776305 | 0.82 | KMT2A (0.43) | MAPTALDH1A1SMN1; SMN2POLBPKM | |
| SCHEMBL9776287 | 0.80 | MAPT (0.47) | MAPTALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL18631013 | 0.74 | MAPT (0.41) | MAPTALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL18631010 | 0.74 | MAPT (0.41) | MAPTALDH1A1SMN1; SMN2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041143-A | N,N'-disubstituted nitro-para-phenylenediamines, and dyeing compositions containing the same | L'OREAL (FR) | 1991-08-20 | — | — | US | disclosed |
| US-4910341-A | Reacting chloroethyl chloroformate with 4-halo-3-nitroaniline in presence of a base; cyclization; alkaline hydrolysis | L'OREAL (FR) | 1990-03-20 | — | — | US | disclosed |