Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9776285 | 0.86 | MAPT (0.50) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL9776302 | 0.84 | MAPT (0.52) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL9776298 | 0.84 | MAPT (0.49) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL9776267 | 0.83 | KMT2A (0.62) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL9776288 | 0.82 | MAPT (0.56) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL9776287 | 0.80 | MAPT (0.47) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL9776275 | 0.76 | MAPT (0.40) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL11316660 | 0.75 | ALDH1A1 (0.53) | HDAC1POLBALDH1A1NPSR1MAPT | |
| SCHEMBL19308367 | 0.74 | CMA1 (0.44) | KMT2AALDH1A1NPSR1MAPTPKM | |
| SCHEMBL1594633 | 0.74 | MAPT (0.56) | HDAC1POLBALDH1A1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041143-A | N,N'-disubstituted nitro-para-phenylenediamines, and dyeing compositions containing the same | L'OREAL (FR) | 1991-08-20 | — | — | US | disclosed |
| US-4910341-A | Reacting chloroethyl chloroformate with 4-halo-3-nitroaniline in presence of a base; cyclization; alkaline hydrolysis | L'OREAL (FR) | 1990-03-20 | — | — | US | disclosed |