Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.81 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.81 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.81 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.81 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.81 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | CDC25A | P30304 | 5/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 5/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 5/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Epipolygodial SCHEMBL29370854 | 0.90 | CHRNB2 (1.00) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| Polygodial SCHEMBL21633831 | 0.90 | CHRNB2 (1.00) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| Polygodial SCHEMBL258239 | 0.90 | CHRNB2 (1.00) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| Epipolygodial SCHEMBL13855685 | 0.90 | CHRNB2 (1.00) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| Epipolygodial SCHEMBL21322435 | 0.90 | CHRNB2 (1.00) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| Polygodial SCHEMBL22658148 | 0.77 | CHRNB2 (0.66) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| SCHEMBL18583214 | 0.76 | CHRNB2 (0.65) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| SCHEMBL18583220 | 0.76 | CHRNB2 (0.65) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| SCHEMBL13692692 | 0.74 | CHRNB2 (0.71) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| SCHEMBL6784016 | 0.74 | CHRNB2 (0.71) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3251191-A | — | — | None | — | — | JP | disclosed |
| JP-H03251191-A | DRIMANE DERIVATIVE HAVING ANTINEOPLASTIC EFFECT | SHIONOGI & CO LTD | 1991-11-08 | — | — | JP | disclosed |