Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 6/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CDK2 | P24941 | 2/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9776573 | 0.82 | PKM (0.62) | PKMPOLBCDK2CDK1CCNB1 | |
| SCHEMBL9521763 | 0.82 | PKM (0.70) | PKMPOLBCDK2CDK1CCNB1 | |
| SCHEMBL9523984 | 0.80 | PKM (0.62) | PKMPOLBCDK2CDK1CCNB1 | |
| SCHEMBL4291141 | 0.78 | CDK2 (0.65) | PKMPOLBCDK2CDK1CCNB1 | |
| SCHEMBL11339041 | 0.78 | CDK2 (0.58) | PKMPOLBCDK2CDK1CCNB1 | |
| SCHEMBL9776539 | 0.78 | PKM (0.60) | PKMPOLBCDK2CDK1CCNB1 | |
| SCHEMBL9525566 | 0.76 | PKM (0.52) | PKMPOLBCDK2CDK1CCNB1 | |
| SCHEMBL9776504 | 0.76 | POLB (0.46) | PKMPOLBCDK2CDK1CCNB1 | |
| SCHEMBL9525562 | 0.76 | PKM (0.52) | PKMPOLBCDK2CDK1CCNB1 | |
| SCHEMBL10373441 | 0.75 | PKM (0.59) | PKMPOLBCDK2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985432-A | 5H-1,3,4-thiadiazolo(3,2-A)pyrimidin-5-one derivatives and agricultural-horticultural fungicide composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0242690-A2 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and agricultural-horticultural fungicide composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-10-28 | — | — | EP | disclosed |