Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Silver. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28972576 | 0.95 | CYP4F2 (0.32) | CYP4F2CYP4A11FFAR3HDAC3HDAC1 | |
| SCHEMBL7906334 | 0.95 | FFAR3 (0.36) | CYP4F2CYP4A11FFAR3HDAC3HDAC1 | |
| SCHEMBL28972718 | 0.95 | CYP4F2 (0.32) | CYP4F2CYP4A11FFAR3HDAC3HDAC1 | |
| SCHEMBL28671830 | 0.95 | CYP4F2 (0.32) | CYP4F2CYP4A11FFAR3HDAC3HDAC1 | |
| Potassium Ion SCHEMBL28681486 | 0.95 | CYP4F2 (0.32) | CYP4F2CYP4A11FFAR3HDAC3HDAC1 | |
| Silver SCHEMBL17797184 | 0.86 | FFAR3 (0.36) | CYP4F2CYP4A11FFAR3HDAC3HDAC1 | |
| SCHEMBL4777919 | 0.80 | FFAR3 (0.41) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4957927 | 0.80 | FFAR3 (0.36) | CYP4F2CYP4A11FFAR3HDAC3HDAC1 | |
| Lithium Ion SCHEMBL18321792 | 0.80 | FFAR3 (0.36) | CYP4F2CYP4A11FFAR3HDAC3HDAC1 | |
| SCHEMBL6818429 | 0.80 | FFAR3 (0.36) | CYP4F2CYP4A11FFAR3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7875214-B2 | A mixture of silver oxide and a silver salt of a hydroxy(s)-containng fatty acid composition. Coating on a substrate of low heat resistance such as Polyethylene Terephthalate and subjected to a low temperature and short-time heat treatment to effect chemical reduction;printed circuits | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2011-01-25 | — | — | US | claimed |
| US-20090085015-A1 | ELECTROCONDUCTIVE COMPOSITION, METHOD FOR FORMING ELECTROCONDUCTIVE FILM, AND ELECTROCONDUCTIVE FILM | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2009-04-02 | — | — | US | claimed |
| US-7875214-B2 | A mixture of silver oxide and a silver salt of a hydroxy(s)-containng fatty acid composition. Coating on a substrate of low heat resistance such as Polyethylene Terephthalate and subjected to a low temperature and short-time heat treatment to effect chemical reduction;printed circuits | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2011-01-25 | — | — | US | disclosed |
| US-20090085015-A1 | ELECTROCONDUCTIVE COMPOSITION, METHOD FOR FORMING ELECTROCONDUCTIVE FILM, AND ELECTROCONDUCTIVE FILM | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2009-04-02 | — | — | US | disclosed |