SCHEMBL977659

SCHEMBL977659

C=CC(=O)NCP(=O)(OCC(C)Cl)OCC(C)Cl

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3658307 0.82 TSHR (0.33) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL491449 0.78 TSHR (0.43) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL977677 0.74 TSHR (0.46) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL27972434 0.74 TSHR (0.34) TSHR
SCHEMBL11324594 0.71
SCHEMBL28433367 0.67 ZDHHC20 (0.48) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL5161553 0.67 TSHR (0.42) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL28344102 0.67 TSHR (0.38) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL11027945 0.66
SCHEMBL167298 0.66 TSHR (0.47) TSHRALDH1A1MAPK1TDP1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112533910-A Monoethylenically unsaturated monomers and their use 博斯蒂克股份公司 2021-03-19 CN claimed
EP-1675880-B1 METHOD FOR PARTIAL OR TOTAL OXIDATION OF ONE OR SEVERAL THIOCARBONYLTHIO ENDS OF A POLYMER OBTAINED BY RADICAL POLYMERISATION CONTROLLED BY REVERSIBLE ADDITION-CLEAVAGE RHODIA CHIMIE SA (FR) 2019-03-13 EP claimed
US-7728088-B2 Synthesis of statistical microgels by means of controlled radical polymerisation RHODIA OPERATIONS (FR) 2010-06-01 US claimed
EP-1527105-B1 SYNTHESIS OF STATISTICAL MICROGELS BY MEANS OF CONTROLLED RADICAL POLYMERISATION RHODIA CHIMIE SA (FR) 2009-02-25 EP claimed
US-7439292-B2 Use of block copolymers bearing phosphate and/or phosphonate functions as adhesion promoters or as protecting agents against the corrosion of a metallic surface RHODIA CHIMIE (FR) 2008-10-21 US claimed
EP-1483344-B1 USE OF BLOCK COPOLYMERS BEARING PHOSPHATE AND/OR PHOSPHONATE FUNCTIONS AS ADHESION PROMOTERS OR AS PROTECTING AGENTS AGAINST THE CORROSION OF A METALLIC SURFACE RHODIA CHIMIE SA (FR) 2008-08-06 EP claimed
EP-1483341-B1 USE OF BLOCK COPOLYMERS BEARING PHOSPHONATE FUNCTIONS AS ADHESION PROMOTERS OR AS PROTECTING AGENTS AGAINST THE CORROSION OF A METALLIC SURFACE RHODIA CHIMIE SA (FR) 2008-05-07 EP claimed
US-20070027266-A1 Oxidizing one or more thiocarbonylthio ends of a polymer resulting from a radical polymerization controlled by reversible addition-fragmentation using thiocarbonylthio by reacting with ozone SPECIALTY OPERATIONS FRANCE (FR) 2007-02-01 US claimed
US-20060106178-A1 Synthesis of statistical microgels by means of controlled radical polymerisation RHODIA CHIMIE (FR) 2006-05-18 US claimed
US-20050181225-A1 Use of block copolymers bearing phosphate and/or phosphonate functions as adhesion promoters or as protecting agents against the corrosion of a metallic surface CHIMIE, RHODIA (FR) 2005-08-18 US claimed
US-20050119386-A1 Use of block copolymers bearing phosphate and/or phosphonate functions as adhesion promoters or as protecting agents against the corrosion of a metallic surface RHODIA CHIMIE (FR) 2005-06-02 US claimed
CN-112533910-B Monoethylenically unsaturated monomers and their use 博斯蒂克股份公司 2024-05-10 CN disclosed
EP-2838816-B1 LOW VOC, WATER-BASED COATING COMPOSITIONS SUITABLE FOR PROTECTING METAL CONTAINING SUBSTRATES INCLUDING FOOD AND BEVERAGE PACKAGES SWIMC LLC (US) 2021-09-08 EP disclosed
CN-112533910-A Monoethylenically unsaturated monomers and their use 博斯蒂克股份公司 2021-03-19 CN disclosed
US-9981287-B2 Low VOC, water-based coating compositions suitable for protecting metal containing substrates including food and beverage packages THE SHERWIN-WILLIAMS COMPANY (US) 2018-05-29 US disclosed
US-7439292-B2 Use of block copolymers bearing phosphate and/or phosphonate functions as adhesion promoters or as protecting agents against the corrosion of a metallic surface RHODIA CHIMIE (FR) 2008-10-21 US disclosed
US-20070027266-A1 Oxidizing one or more thiocarbonylthio ends of a polymer resulting from a radical polymerization controlled by reversible addition-fragmentation using thiocarbonylthio by reacting with ozone SPECIALTY OPERATIONS FRANCE (FR) 2007-02-01 US disclosed
US-20060106178-A1 Synthesis of statistical microgels by means of controlled radical polymerisation RHODIA CHIMIE (FR) 2006-05-18 US disclosed
US-20050181225-A1 Use of block copolymers bearing phosphate and/or phosphonate functions as adhesion promoters or as protecting agents against the corrosion of a metallic surface CHIMIE, RHODIA (FR) 2005-08-18 US disclosed
US-20050119386-A1 Use of block copolymers bearing phosphate and/or phosphonate functions as adhesion promoters or as protecting agents against the corrosion of a metallic surface RHODIA CHIMIE (FR) 2005-06-02 US disclosed