Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 12/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 7/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543225 | 0.90 | SRD5A1 (0.38) | SRD5A1CYP19A1MBOAT4SRD5A2 | |
| SCHEMBL9618179 | 0.87 | SRD5A1 (0.42) | SRD5A1CYP19A1MBOAT4SRD5A2 | |
| SCHEMBL4807027 | 0.84 | CYP19A1 (0.41) | SRD5A1CYP19A1MBOAT4SRD5A2 | |
| SCHEMBL7643432 | 0.84 | CYP19A1 (0.41) | SRD5A1CYP19A1MBOAT4SRD5A2 | |
| SCHEMBL9318599 | 0.79 | CYP19A1 (0.39) | SRD5A1CYP19A1MBOAT4SRD5A2 | |
| SCHEMBL8677534 | 0.79 | CYP19A1 (0.35) | SRD5A1CYP19A1MBOAT4SRD5A2 | |
| SCHEMBL9776615 | 0.78 | SRD5A1 (0.41) | SRD5A1MBOAT4SRD5A2 | |
| SCHEMBL11410578 | 0.77 | CYP19A1 (0.38) | SRD5A1CYP19A1MBOAT4SRD5A2 | |
| SCHEMBL5109018 | 0.75 | CYP19A1 (0.44) | SRD5A1CYP19A1MBOAT4SRD5A2 | |
| SCHEMBL8823382 | 0.74 | SRD5A2 (0.39) | SRD5A1CYP19A1MBOAT4SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462668-A2 | New 17beta-aminobenzoyl-4-aza-5alpha-androst-1-en-3-ones as benign prostatic hypertrophy agents | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |
| US-5061802-A | 17β-aminobenzoyl-4-aza-5α-androst-1-en-3-ones as benign prostatic hypertrophy agents | MERCK & CO. INC. (US) | 1991-10-29 | — | — | US | disclosed |