Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | HSD3B1 | P14060 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643432 | 1.00 | CYP19A1 (0.41) | CYP19A1MBOAT4GRIN1GRIN2BCDK5 | |
| SCHEMBL9318599 | 0.88 | CYP19A1 (0.39) | CYP19A1MBOAT4GRIN1GRIN2BNR1I3 | |
| SCHEMBL11410578 | 0.85 | CYP19A1 (0.38) | CYP19A1MBOAT4GRIN1GRIN2BLMNA | |
| SCHEMBL9618179 | 0.85 | SRD5A1 (0.42) | CYP19A1MBOAT4GRIN1GRIN2BSRD5A1 | |
| SCHEMBL9776609 | 0.84 | SRD5A1 (0.39) | CYP19A1MBOAT4SRD5A1SRD5A2 | |
| SCHEMBL5109018 | 0.83 | CYP19A1 (0.44) | CYP19A1MBOAT4GRIN1GRIN2BCDK5 | |
| SCHEMBL9543225 | 0.83 | SRD5A1 (0.38) | CYP19A1MBOAT4SRD5A1SRD5A2 | |
| SCHEMBL8823382 | 0.82 | SRD5A2 (0.39) | CYP19A1MBOAT4GRIN1GRIN2BNR1I3 | |
| SCHEMBL8823386 | 0.82 | SRD5A2 (0.39) | CYP19A1MBOAT4GRIN1GRIN2BNR1I3 | |
| SCHEMBL5580929 | 0.82 | CYP19A1 (0.35) | CYP19A1MBOAT4GRIN1GRIN2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008101308-A1 | PROCESS FOR THE PREPARATION OF 17-N-SUBSTITUTED-CARBAMOYL-4-AZA-ANDROST-1 -EN-3-ONES | APOTEX PHARMACHEM INC. (CA) | 2008-08-28 | — | — | WO | disclosed |