Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.87 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2168586 | 1.00 | MAPK1 (0.87) | MAPK1LMNAMAPTRAB9AMEN1 | |
| SCHEMBL9248915 | 1.00 | MAPK1 (0.87) | MAPK1LMNAMAPTRAB9AMEN1 | |
| SCHEMBL9457019 | 0.93 | MAPK1 (1.00) | MAPK1LMNAMAPTRAB9AMEN1 | |
| Hydroquinone SCHEMBL9777901 | 0.93 | MAPK1 (1.00) | MAPK1LMNAMAPTRAB9AMEN1 | |
| Hydroquinone SCHEMBL10635396 | 0.93 | MAPK1 (1.00) | MAPK1LMNAMAPTRAB9AMEN1 | |
| SCHEMBL333466 | 0.93 | MAPK1 (1.00) | MAPK1LMNAMAPTRAB9AMEN1 | |
| SCHEMBL9777896 | 0.93 | MAPK1 (1.00) | MAPK1LMNAMAPTRAB9AMEN1 | |
| Hydroquinone SCHEMBL9777898 | 0.91 | MAPK1 (0.95) | MAPK1LMNAMAPTRAB9AMEN1 | |
| SCHEMBL29217821 | 0.91 | MAPK1 (0.95) | MAPK1LMNAMAPTRAB9AMEN1 | |
| SCHEMBL30496095 | 0.91 | MAPK1 (0.95) | MAPK1LMNAMAPTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5053477-A | Reacting aromatic dihydroxy compound and aromatic dihalogeno compound containing a keto group in N-alkylcaprolactam solvent with mixture of alkali metal compounds including a carbonate | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-01 | — | — | US | disclosed |