Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11324371 | 0.86 | MEN1 (0.55) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL3346423 | 0.86 | MEN1 (0.55) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL11778968 | 0.86 | MEN1 (0.55) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL10356688 | 0.85 | — | — | |
| SCHEMBL11516067 | 0.85 | MEN1 (0.35) | MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL11515615 | 0.85 | MEN1 (0.35) | MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL11330126 | 0.80 | TSHR (0.48) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL8778909 | 0.80 | TSHR (0.48) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL11515710 | 0.78 | — | — | |
| SCHEMBL1725816 | 0.77 | MEN1 (0.60) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5000866-A | Antifreeze compositions containing alkane tetracarboxylic acid for use with hard water | FIRST BRANDS CORPORATION (US) | 1991-03-19 | — | — | US | disclosed |
| US-4725405-A | Organosiloxane-silicate copolymer antifreeze composition with nitrate corrosion inhibitor | FIRST BRANDS CORPORATION (US) | 1988-02-16 | — | — | US | disclosed |
| US-4676919-A | Low pH-buffered silicon/silicate antifreeze concentrates | FIRST BRANDS CORPORATION (US) | 1987-06-30 | — | — | US | disclosed |
| US-4664833-A | AUTOMOBILE COOLANTS | UNION CARBIDE CORPORATION (US) | 1987-05-12 | — | — | US | disclosed |